Relationship between tumor thickness on images and cellular dissociation grading composing of tumor budding and cell nest size in early tongue cancer
Relationship between tumor thickness on images and cellular dissociation grading composing of tumor budding and cell nest size in early tongue cancer
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早期舌癌图像上肿瘤厚度与肿瘤出芽和细胞巢大小的细胞解离分级的关系
DOI：
10.1002/osi2.1180
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发表时间：
2023
影响因子：
0.5
通讯作者：
Ikebe Tetsuro
中科院分区：
文献类型：
--
作者：
Yokoo Yoshinobu;Yuasa Kenji;Ohno Jun;Ikebe Tetsuro
目的本研究的目的是阐明在I期和II期舌口腔鳞状细胞癌（OSCC）中使用增强CT、增强T1加权MR成像和超声检查（US）进行的图像分析是否与基于肿瘤出芽分级和细胞巢大小的细胞解离分级（CDG）相关。 方法 17例T1N0M0和T2N0M0舌 回顾性纳入完成 1 年以上随访的 OSCC。 16例病例均获得满意的数据，包括增强CT图像、增强T1加权MR图像、超声图像以及组织病理学标本，并由口腔病理学家、口腔放射科医生和口腔颌面外科医生的专家进行分析。结果超声图像上的肿瘤厚度（TT）与增强CT图像或增强后的TT之间的差异 较低肿瘤出芽级别病例的 T1 加权 MR 图像比较高出芽级别病例更大。很可能，这种图像测量的 TT 差异在较大的巢箱中比在较小的巢箱中更大。迟发性淋巴结转移的发生与CT-US或MRI-US的TT差异较小以及CDG评分较高（≥5分）有关。所有迟发性淋巴结转移病例CDG评分≥5分。结论增强CT/MR成像与超声成像的TT差异可以预测细胞解离活性和淋巴结转移。
PurposeThe purpose of this study is to clarify whether the image analysis using contrast enhanced CT, contrast enhanced T1‐weighted MR imaging and ultrasonography (US), is related with the cellular dissociation grade (CDG) based on tumor budding grade and cell nest size in stage I and II tongue oral squamous cell carcinoma (OSCC).MethodSeventeen cases of T1N0M0 and T2N0M0 tongue OSCC with the completion of more than 1‐year follow‐up were retrospectively enrolled. The satisfactory data, including contrast enhanced CT images, contrast enhanced T1‐weighted MR images, and US images as well as histopathological specimens could be taken from 16 cases and analyzed by the specialists of oral pathologist, oral radiologist, and oral and maxillofacial surgeon.ResultsThe differences between tumor thickness (TT) on US images and TT on contrast enhanced CT images or contrast enhanced T1‐weighted MR images were larger in the lower tumor budding grade cases rather than in the higher budding grade. Likely, such image‐measured TT differences were larger in the bigger nest cases than in the smaller nest cases. The occurrence of delayed nodal metastasis was related to the small TT differences of CT–US or MRI–US and the higher CDG score (≧5 points). All the cases with delayed nodal metastasis were CDG score ≧5 points.ConclusionsTT differences between on contrast enhanced CT/MR imaging, and US imaging may predict the cell dissociation activity and nodal metastasis.
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影响因子：
2.1
作者：
Rahman N;MacNeill M;Wallace W;Conn B
通讯作者：
Conn B
口腔鳞状细胞癌侵袭和淋巴结转移模式的表达谱。
DOI：
--
发表时间：
2007
期刊：
影响因子：
--
作者：
Kondoh N ;et. al.
通讯作者：
et. al.
DOI：
--
发表时间：
1973
期刊：
Acta radiologica: therapy, physics, biology
影响因子：
--
作者：
P. Jakobsson;C. Eneroth;D. Killander;G. Moberger;B. Mårtensson
通讯作者：
B. Mårtensson
口腔鳞状细胞癌恶性肿瘤组织学分类和分级的方法学研究。
DOI：
--
发表时间：
1984
期刊：
Scandinavian journal of dental research
影响因子：
--
作者：
G. Anneroth;L. S. Hansen
通讯作者：
L. S. Hansen
影响因子：
6.4
作者：
Seki, Mai;Sano, Takaaki;Oyama, Tetsunari
通讯作者：
Oyama, Tetsunari