Arsenic in drinking water and peripheral nerve conduction velocity among residents of a chronically arsenic-affected area in Inner Mongolia.
Arsenic in drinking water and peripheral nerve conduction velocity among residents of a chronically arsenic-affected area in Inner Mongolia.
复制标题
DOI：
10.2188/jea.16.207
复制
发表时间：
2006-09
影响因子：
4.7
通讯作者：
Japan Inner Mongolia Arsenic Pollution Study Group
中科院分区：
文献类型：
--
作者：
Fujino Y;Guo X;Shirane K;Liu J;Wu K;Miyatake M;Tanabe K;Kusuda T;Yoshimura T;Japan Inner Mongolia Arsenic Pollution Study Group
目前尚不清楚慢性摄入饮用水中的砷是否会影响周围神经系统。我们用肌电图仪检测了砷暴露对神经传导速度的影响。中国，对内蒙古河套平原某砷污染村人群进行了横断面调查。143名居民中的134人(93.7%)参加了研究，并以某低砷暴露村47名居民中的36人(76.6%)为对照组。在参与者中，使用了年龄为18岁的受砷影响村庄的109名居民和低砷暴露村庄的32名居民进行分析。一位内科专家进行了皮肤检查，并用肌电图仪检测了正中神经传导速度。测定管井水和尿砷含量。砷污染村管井水砷平均水平为158.3μg/L，低砷暴露村为5.3μg/L。管井水砷含量、尿砷水平、管井使用时间与其运动神经传导速度和感觉神经传导速度均值无显著差异。此外，砷皮肤病患者和非砷皮肤病患者的平均红细胞体积和血细胞体积无明显差异，平均血细胞体积分别为52.8m/S(SD6.3)和54.6m/S(5.2%)(P=0.206)。这些发现表明，慢性饮用水砷中毒不太可能影响神经传导速度，至少在本研究检查的饮用水中砷的范围内是这样。
It remains unclear whether chronic ingestion of arsenic in drinking water affects the peripheral nervous system. We examined the effects of arsenic exposure on nerve conduction velocity using electromyography. A cross-sectional study was conducted of a population living in an arsenic-affected village in Hetao Plain, Inner Mongolia, China. A total of 134 (93.7%) of 143 inhabitants took part in the study, and 36 (76.6%) of 47 inhabitants in a low-arsenic exposed village were recruited as a control group. Of the participants, 109 inhabitants in the arsenic-affected village and 32 in the low-arsenic exposed village aged ≥18 years were used for the analyses. An expert physician performed skin examinations, and median nerve conduction velocity was examined by electromyography. Arsenic levels in tube-well water and urine were measured. A mean level of arsenic in tube-well water in the arsenic-affected village was 158.3μg/L, while that in the low-arsenic exposed village was 5.3μg/L. No significant differences in the means of the motor nerve conduction velocity (MCV) and sensory nerve conduction velocity (SCV) were observed in relation to arsenic levels in tube wells, urine, and the duration of tube-well use. Further, no differences in mean MCV or SCV were found between the subjects with and without arsenic dermatosis, with mean SCV of 52.8 m/s (SD 6.3) in those without and 54.6 m/s (5.2) in subjects with arsenic dermatosis (p=0.206). These findings suggest that chronic arsenic poisoning from drinking water is unlikely to affect nerve conduction velocity, at least within the range of arsenic in drinking water examined in the present study.
登录
查看更多内容
DOI：
10.1081/ese-120016887
发表时间：
2003-01-01
影响因子：
2.1
作者：
Mukherjee, SC;Rahman, MM;Chakraborti, D
通讯作者：
Chakraborti, D
影响因子：
158.5
作者：
HEYMAN, A;PFEIFFER, JB;TAYLOR, HM
通讯作者：
TAYLOR, HM
影响因子：
3.3
作者：
Matsubara, T
通讯作者：
Matsubara, T
由于饮用水中摄入的无机砷而导致的肝脏，肺，膀胱和肾脏的癌症潜力。
影响因子：
8.8
作者：
Chen, C J;Chen, C W;Wu, M M;Kuo, T L
通讯作者：
Kuo, T L
DOI：
10.1080/00039896.1983.10543990
发表时间：
1983-01-01
期刊：
ARCHIVES OF ENVIRONMENTAL HEALTH
影响因子：
--
作者：
KREISS, K;ZACK, MM;COX, DH
通讯作者：
COX, DH