Circadian thermosensitive characteristics of suprachiasmatic neurons in vitro.
Circadian thermosensitive characteristics of suprachiasmatic neurons in vitro.
复制标题
体外视交叉上神经元的昼夜温敏特性。
DOI:
10.1152/ajpregu.1994.266.6.r1876
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
Boulant,JA
中科院分区:
文献类型:
--
作者:
Derambure,PS;Boulant,JA
The circadian pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) affects several regulatory systems, including body temperature. To study circadian changes in the firing rate and thermosensitivity of SCN neurons, single-unit activity was recorded from the dorsomedial and ventrolateral SCN in frontal slices of rat hypothalamus during changes in tissue temperature. When analyzed according to circadian time (CT), 305 neurons were characterized by firing rate and 208 neurons were characterized by thermosensitivity. Circadian firing-rate changes were evident only in the dorsomedial SCN, with peak firing rates occurring during the subjective day. Circadian changes in SCN neuronal thermosensitivity also were observed, but the greatest thermosensitivity occurred during the subjective night. Increased thermosensitivity was most dramatic in the ventrolateral SCN, where > 40% of the neurons were warm sensitive in the CT 16- to 20-h period. These changes in neuronal thermosensitivity may reflect interactions between body temperature and circadian rhythms.
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影响因子:
2.9
作者:
K. Ptashne;H. Hsueh;F. Stockdale
通讯作者:
F. Stockdale
DOI:
--
发表时间:
1978
期刊:
影响因子:
--
作者:
W. Schrader;B. O’Malley
通讯作者:
B. O’Malley
影响因子:
56.9
作者:
CARPENTER, G
通讯作者:
CARPENTER, G
DOI:
--
发表时间:
1983
期刊:
Biochemical and Biophysical Research Communications - BBRC
影响因子:
--
作者:
Sudhir K. Sinha;A. A. Yunis
通讯作者:
A. A. Yunis
影响因子:
4
作者:
BEARDMORE, JM;RICHARDS, RC
通讯作者:
RICHARDS, RC