Targeting the perpetrator: breast cancer stem cell therapeutics.
Targeting the perpetrator: breast cancer stem cell therapeutics.
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DOI:
10.2174/138945010792006843
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发表时间:
2010-09
影响因子:
3.2
通讯作者:
Behbod F
中科院分区:
文献类型:
--
作者:
Pal A;Valdez KE;Carletti MZ;Behbod F
The hypothesis that tumors may originate from a rare population of cancer stem cells (CSCs) has gained tremendous popularity in recent years and is supported extensively by several pioneering works. Cancer therapies targeting CSCs have unlimited potential for relapse free survival of cancer patients. As a result, knowledge of biological pathways that govern CSCs is very important and this review is focused on the biology of CSCs and recent advances in therapeutic approaches targeting them.
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