Radiographic trabecular 2D and 3D parameters of proximal femoral bone cores correlate with each other and with yield stress.
Radiographic trabecular 2D and 3D parameters of proximal femoral bone cores correlate with each other and with yield stress.
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DOI：
10.1007/s00198-009-0908-z
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发表时间：
2009-11
影响因子：
4
通讯作者：
Lang, P.
中科院分区：
文献类型：
--
作者：
Steines, D.;Liew, S. -W.;Arnaud, C.;Vargas-Voracek, R.;Nazarian, A.;Mueller, R.;Snyder, B.;Hess, P.;Lang, P.
我们比较了身体股骨近端骨芯的二维(2D)投影放射学图像中的骨小梁模式的形态测量值与三维(3D)μCT图像中概念上相同的测量值。7具身体股骨近端提供了来自7个区域的47个切除髓核。用提取骨小梁模式的软件处理这些核心的数字化X线片。将它们的分布、几何形状和连通性的测量结果与μCT获得的类似定义的3D参数进行比较。还研究了二维和三维测量与屈服应力的关系。2D测量值与使用3DμCT获得的概念上等价的测量值有很强的相关性。在所有情况下，相关系数都很高，从r=0.84(p<；0.001)到r=0.93(p<；0.001)。二维和三维测量与岩芯屈服应力的相关系数也很高(r分别为0.6和0.82p<；0.001)。这些发现提供了相关的生物力学证据，支持从股骨近端X线平片图像中提取的2D微观结构参数与概念上相同的相同核心的3D微观结构测量结果的定性相似性。
We compared morphometric measurements of trabecular patterns in two-dimensional (2D) projection radiographic images of cores from cadaver proximal femoral bones with conceptually equivalent measurements from three-dimensional (3D) μCT images. Seven cadaver proximal femora provided 47 excised cores from seven regions. Digitized radiographs of those cores were processed with software that extracts trabecular patterns. Measurements of their distribution, geometry, and connectivity were compared with 3D parameters of similar definition derived from μCT of those cores. The relationship between 2D and 3D measurements and yield stress was also examined. 2D measurements strongly correlated with conceptually equivalent measurements obtained using 3D μCT. In all cases, the correlation coefficients were high, ranging from r=0.84 (p<0.001) to r=0.93 (p<0.001). The correlation coefficients between 2D and 3D measurements and yield stress of the cores were also high (r=0.60 and 0.82, p<0.001 respectively). These findings provide correlative and biomechanical evidence supporting the qualitative similarity of 2D microstructural parameters extracted from plain proximal femoral core X-ray images to conceptually equivalent 3D microstuctural measurements of those same cores.
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影响因子：
3.8
作者：
CALIGIURI, P;GIGER, ML;FAVUS, M
通讯作者：
FAVUS, M
影响因子：
6.2
作者：
Burge, Russel;Dawson-Hughes, Bess;Tosteson, Anna
通讯作者：
Tosteson, Anna
影响因子：
4.2
作者：
Lochmueller, E.-M.;Kristin, J.;Eckstein, F.
通讯作者：
Eckstein, F.
影响因子：
3.8
作者：
Ouyang, XL;Majumdar, S;Genant, HK
通讯作者：
Genant, HK
影响因子：
4.1
作者：
PARFITT, AM
通讯作者：
PARFITT, AM