Kidney development: from ureteric bud formation to branching morphogenesis.
Kidney development: from ureteric bud formation to branching morphogenesis.
复制标题
肾脏发育:从输尿管芽形成到分支形态发生。
DOI:
10.1016/j.gde.2009.09.003
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发表时间:
2009-10
影响因子:
4
通讯作者:
Michos, Odysse
中科院分区:
文献类型:
--
作者:
Michos, Odysse
Epithelial branching morphogenesis is critical to formation of various organs such as the vasculature, mammary glands, lungs and kidneys in vertebrate embryos. One fascinating aspect of branching morphogenesis is to understand how a simple epithelial tube grows by reiterative branching to form a complex epithelial tree structure. Recent studies combining mouse genetics and chimeric analysis with live imaging have uncovered the molecular networks and interactions that govern kidney branching morphogenesis. This review focuses on ureteric bud formation and epithelial branching during kidney development. The invasion of the metanephric mesenchyme by the ureteric bud is a fundamental step towards establishing the cyto-architecture of the kidney and determining the number of nephrons, which form the filtration units of the adult kidney.
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影响因子:
11.8
作者:
Carroll, TJ;Park, JS;McMahon, AP
通讯作者:
McMahon, AP
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4.6
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Majumdar, A;Vainio, S;McMahon, AP
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McMahon, AP
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13.6
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Hartwig, Sunny;Bridgewater, Darren;Rosenblum, Norman D.
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Rosenblum, Norman D.
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4.5
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Grote D;Boualia SK;Souabni A;Merkel C;Chi X;Costantini F;Carroll T;Bouchard M
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Bouchard M
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1.5
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Chi, Xuan;Hadjantonakis, Anna-Katerina;Wu, Zaiqi;Hyink, Deborah;Costantini, Frank
通讯作者:
Costantini, Frank