Chemical Interventions for the Opioid Crisis: Key Advances and Remaining Challenges.

Chemical Interventions for the Opioid Crisis: Key Advances and Remaining Challenges.
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DOI:
10.1021/jacs.8b09756
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发表时间:
2019-02-06
影响因子:
15
通讯作者:
Janda, Kim D.
Janda, Kim D.
中科院分区:
化学1区
文献类型:
--
作者:
Olson, Margaret E.;Eubanks, Lisa M.;Janda, Kim D.

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The present United States opioid crisis requires urgent and innovative scientific intervention. This perspective highlights a role for the chemical sciences by expounding upon three key research areas identified as priorities by the National Institute on Drug Abuse (NIDA). Specifically, important advances in chemical interventions for overdose reversal, strategies for opioid use disorder (OUD) treatment, including immunopharmacotherapies, and next-generation alternatives for pain management will be discussed. Ultimately, progress made will be presented in light of remaining challenges for the field.
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