The relationship of docosahexaenoic acid (DHA) with learning and behavior in healthy children: a review.
The relationship of docosahexaenoic acid (DHA) with learning and behavior in healthy children: a review.
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DOI：
10.3390/nu5072777
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发表时间：
2013-07-19
期刊：
影响因子：
5.9
通讯作者：
Salem N Jr
中科院分区：
文献类型：
--
作者：
Kuratko CN;Barrett EC;Nelson EB;Salem N Jr
童年是大脑生长和成熟的时期。长链 omega-3 脂肪酸二十二碳六烯酸 (DHA) 是大脑中的主要脂质，被认为对正常大脑功能至关重要。在动物中，大脑 DHA 含量低会导致学习和行为受损。对于婴儿来说，DHA 对于最佳视觉和认知发育非常重要。幼儿和儿童通常摄入的 DHA 较低，一些研究表明，补充包括 DHA 在内的多不饱和脂肪酸可以改善认知和行为。本次综述的目的是确定和评估关于 DHA 与健康学龄儿童学习和行为指标之间关系的现有知识。对文献进行系统检索，确定了 15 篇相关出版物供审查。搜索发现研究的目的和设计各不相同，并且关于 DHA 摄入量或生物标志物状态对特定认知测试的治疗效果没有一致的结论。然而，针对大脑活动的研究报告了补充 DHA 的益处，并且超过一半的研究报告了 DHA 或长链 omega-3 脂肪酸在至少一个认知或行为领域的有利作用。研究还表明 DHA 在学校表现中发挥着重要作用。
Childhood is a period of brain growth and maturation. The long chain omega-3 fatty acid, docosahexaenoic acid (DHA), is a major lipid in the brain recognized as essential for normal brain function. In animals, low brain DHA results in impaired learning and behavior. In infants, DHA is important for optimal visual and cognitive development. The usual intake of DHA among toddlers and children is low and some studies show improvements in cognition and behavior as the result of supplementation with polyunsaturated fatty acids including DHA. The purpose of this review was to identify and evaluate current knowledge regarding the relationship of DHA with measures of learning and behavior in healthy school-age children. A systematic search of the literature identified 15 relevant publications for review. The search found studies which were diverse in purpose and design and without consistent conclusions regarding the treatment effect of DHA intake or biomarker status on specific cognitive tests. However, studies of brain activity reported benefits of DHA supplementation and over half of the studies reported a favorable role for DHA or long chain omega-3 fatty acids in at least one area of cognition or behavior. Studies also suggested an important role for DHA in school performance.
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影响因子：
11
作者：
Bloch, M. H.;Hannestad, J.
通讯作者：
Hannestad, J.
影响因子：
4.7
作者：
Bakker, EC;Ghys, AJA;Hornstra, G
通讯作者：
Hornstra, G
影响因子：
2.5
作者：
Birch, Eileen E.;Garfield, Sharon;Hoffman, Dennis
通讯作者：
Hoffman, Dennis
学龄前年份的大脑发育。
影响因子：
5.8
作者：
Brown, Timothy T.;Jernigan, Terry L.
通讯作者：
Jernigan, Terry L.
DOI：
10.1016/j.plefa.2009.05.024
发表时间：
2009-08
期刊：
Prostaglandins, leukotrienes, and essential fatty acids
影响因子：
--
作者：
Bazan NG
通讯作者：
Bazan NG