Recognition of CD1d-restricted antigens by natural killer T cells.
Recognition of CD1d-restricted antigens by natural killer T cells.
复制标题
DOI:
10.1038/nri3328
复制
发表时间:
2012-12
期刊:
影响因子:
--
通讯作者:
中科院分区:
文献类型:
--
作者:
Natural killer T (NKT) cells are innate-like T cells that rapidly produce a variety of cytokines following T cell receptor (TCR) activation and can shape the immune response in many different settings. There are two main NKT cell subsets: type I NKT cells are typically characterized by the expression of a semi-invariant TCR, whereas the TCRs expressed by type II NKT cells are more diverse. This Review focuses on the defining features and emerging generalities regarding how NKT cells specifically recognize self, microbial and synthetic lipid-based antigens that are presented by CD1d. Such information is vitally important to better understand, and fully harness, the therapeutic potential of NKT cells.
登录
查看更多内容
影响因子:
15.9
作者:
Chang, Ya-Jen;Kim, Hye Young;Umetsu, Dale T.
通讯作者:
Umetsu, Dale T.
影响因子:
30.5
作者:
Brennan, Patrick J.;Tatituri, Raju V. V.;Brigl, Manfred;Kim, Edy Y.;Tuli, Amit;Sanderson, Joseph P.;Gadola, Stephan D.;Hsu, Fong-Fu;Besra, Gurdyal S.;Brenner, Michael B.
通讯作者:
Brenner, Michael B.
DOI:
10.1084/jem.182.4.993
发表时间:
1995-10-01
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Cardell S;Tangri S;Chan S;Kronenberg M;Benoist C;Mathis D
通讯作者:
Mathis D
影响因子:
15.3
作者:
Agea, Elisabetta;Russano, Anna;Bistoni, Onelia;Mannucci, Roberta;Nicoletti, Ildo;Corazzi, Lanfranco;Postle, Anthony D;De Libero, Gennaro;Porcelli, Steven A;Spinozzi, Fabrizio
通讯作者:
Spinozzi, Fabrizio
影响因子:
15.3
作者:
Brossay, L;Chioda, M;Burdin, N;Koezuka, Y;Casorati, G;Dellabona, P;Kronenberg, M
通讯作者:
Kronenberg, M