Clinical and immunological characteristics in COVID-19 convalescent patients.
Clinical and immunological characteristics in COVID-19 convalescent patients.
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DOI：
10.1007/s10096-021-04360-w
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发表时间：
2021-12
期刊：
影响因子：
--
通讯作者：
Wang X
中科院分区：
文献类型：
--
作者：
Su Z;Hu W;Liu Q;Zhang Y;Chen T;Zhou Y;Zhang Z;Chen Y;Yang R;Xiong Y;Wang X
The humoral and cellular immunity of convalescent COVID-19 patients is involved in pathogenesis and vaccine immunity. In this study, through CoV-psV neutralization assay and IFN-γ ELISpot testing in 30 cases of COVID-19 patients after 9 months post-SARS-CoV-2 infection, it found that the ratio of memory/naive CD4+ T lymphocytes cells and levels of anti-SARS-CoV-2-IgM and RBD-IgM were slightly but significantly higher in COVID-19 severe convalescent patients than that in non-severe patients. The specific cellular and humoral immunity against SARS-CoV-2 were detectable, regardless of the severity of the disease in the acute phase. This information may help understanding the immune status after SARS-CoV-2 infection.
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Ebinger JE;Fert-Bober J;Printsev I;Wu M;Sun N;Prostko JC;Frias EC;Stewart JL;Van Eyk JE;Braun JG;Cheng S;Sobhani K
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DOI：
10.15557/pimr.2020.0003
发表时间：
2020-01-01
影响因子：
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32.4
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