Reduced-FOV excitation decreases susceptibility artifact in diffusion-weighted MRI with endorectal coil for prostate cancer detection.
Reduced-FOV excitation decreases susceptibility artifact in diffusion-weighted MRI with endorectal coil for prostate cancer detection.
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DOI：
10.1016/j.mri.2014.08.040
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发表时间：
2015-01
影响因子：
2.5
通讯作者：
Noworolski, Susan
中科院分区：
文献类型：
--
作者：
Korn, Natalie;Kurhanewicz, John;Banerjee, Suchandrima;Starobinets, Olga;Saritas, Emine;Noworolski, Susan
本研究的目的是确定由缩小视野(RFOV)扩散加权成像(DWI)技术生成的前列腺MR表观扩散系数(ADC)图的图像失真是否比传统的DWI序列(CONV)小，并确定rFOV ADC肿瘤对比度是否与CONV序列一样高或更好。50例患者接受了3T磁共振检查。使用b=600，0 S/mm~2获得Conv和rFOV(利用2D、回波平面、矩形选择的RF脉冲)序列。由三个独立的观察者对变形进行0-4的视觉评分，并使用ADC图和T2加权图像之间的直肠壁弯曲的差异来定量测量变形。RFOV序列的失真分数较低(p<；0.012，Wilcoxon符号等级检验，n=50)，并且不同观察者之间失真分数的差异没有显著差异(p=0.99，Kruskal-Wallis等级和检验)。直肠曲度的差值rFOV ADC图(26±10%)小于cVADC图(34±13%)(p<；0.011，学生t检验)。在17例未经治疗并经活检证实的前列腺癌患者中，rFOV序列的肿瘤对比度(44.0%)显著高于conv序列(35.9%)(p<；0.0012，学生t检验)。RFOV序列的敏感性伪影显著降低，肿瘤与正常组织的对比度显著增强。
The purpose of this study was to determine if image distortion is less in prostate MR apparent diffusion coefficient (ADC) maps generated from a reduced-field-of-view (rFOV) diffusion-weighted-imaging (DWI) technique than from a conventional DWI sequence (CONV), and to determine if the rFOV ADC tumor contrast is as high as or better than that of the CONV sequence. Fifty patients underwent a 3T MRI exam. CONV and rFOV (utilizing a 2D, echo-planar, rectangularly-selective RF pulse) sequences were acquired using b=600, 0 s/mm2. Distortion was visually scored 0–4 by three independent observers and quantitatively measured using the difference in rectal wall curvature between the ADC maps and T2-weighted images. Distortion scores were lower with the rFOV sequence (p<0.012, Wilcoxon Signed-Rank Test, n=50), and difference in distortion scores did not differ significantly among observers (p=0.99, Kruskal-Wallis Rank Sum Test). The difference in rectal curvature was less with rFOV ADC maps (26±10%) than CONV ADC maps (34±13%) (p<0.011, student’s t-test). In seventeen patients with untreated, biopsy confirmed prostate cancer, the rFOV sequence afforded significantly higher ADC tumor contrast (44.0%) than the CONV sequence (35.9%), (p<0.0012, student’s t-test). The rFOV sequence yielded significantly decreased susceptibility artifact and significantly higher contrast between tumor and healthy tissue.
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影响因子：
3.3
作者：
Mazaheri, Yousef;Vargas, H. Alberto;Hricak, Hedvig
通讯作者：
Hricak, Hedvig
影响因子：
19.7
作者：
Hambrock, Thomas;Somford, Diederik M.;Barentsz, Jelle O.
通讯作者：
Barentsz, Jelle O.
影响因子：
5
作者：
Kim, Chan Kyo;Park, Byung Kwan;Kim, Bohyun
通讯作者：
Kim, Bohyun
影响因子：
4.4
作者：
Noworolski, Susan M.;Crane, Jason C.;Kurhanewicz, John
通讯作者：
Kurhanewicz, John
DOI：
10.1038/nrurol.2009.27
发表时间：
2009-04
期刊：
Nature reviews. Urology
影响因子：
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作者：
通讯作者：
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