Solanum americanum genome-assisted discovery of immune receptors that detect potato late blight pathogen effectors.
Solanum americanum genome-assisted discovery of immune receptors that detect potato late blight pathogen effectors.
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DOI:
10.1038/s41588-023-01486-9
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发表时间:
2023-09
期刊:
影响因子:
30.8
通讯作者:
Jones, Jonathan D. G.
中科院分区:
文献类型:
--
作者:
Lin, Xiao;Jia, Yuxin;Heal, Robert;Prokchorchik, Maxim;Sindalovskaya, Maria;Olave-Achury, Andrea;Makechemu, Moffat;Fairhead, Sebastian;Noureen, Azka;Heo, Jung;Witek, Kamil;Smoker, Matthew;Taylor, Jodie;Shrestha, Ram-Krishna;Lee, Yoonyoung;Zhang, Chunzhi;Park, Soon Ju;Sohn, Kee Hoon;Huang, Sanwen;Jones, Jonathan D. G.
Potato (Solanum tuberosum) and tomato (Solanum lycopersicon) crops suffer severe losses to late blight caused by the oomycete pathogen Phytophthora infestans. Solanum americanum, a relative of potato and tomato, is globally distributed and most accessions are highly blight resistant. We generated high-quality reference genomes of four S. americanum accessions, resequenced 52 accessions, and defined a pan-NLRome of S. americanum immune receptor genes. We further screened for variation in recognition of 315P. infestans RXLR effectors in 52 S. americanum accessions. Using these genomic and phenotypic data, we cloned three NLR-encoding genes, Rpi-amr4, R02860 and R04373, that recognize cognate P. infestans RXLR effectors PITG_22825 (AVRamr4), PITG_02860 and PITG_04373. These genomic resources and methodologies will support efforts to engineer potatoes with durable late blight resistance and can be applied to diseases of other crops. High-quality genome assemblies of four Solanum Americanum accessions lead to the identification of three NLR-encoding genes, Rpi-amr4, R02860 and R04373, that recognize potato late blight pathogen Phytophthora infestans effectors.
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DOI:
10.1111/tpj.12307
发表时间:
2013-11
期刊:
The Plant journal : for cell and molecular biology
影响因子:
--
作者:
Jupe F;Witek K;Verweij W;Sliwka J;Pritchard L;Etherington GJ;Maclean D;Cock PJ;Leggett RM;Bryan GJ;Cardle L;Hein I;Jones JD
通讯作者:
Jones JD
影响因子:
4.5
作者:
通讯作者:
--
影响因子:
48
作者:
Cheng H;Concepcion GT;Feng X;Zhang H;Li H
通讯作者:
Li H
影响因子:
5.3
作者:
Andolfo G;Jupe F;Witek K;Etherington GJ;Ercolano MR;Jones JD
通讯作者:
Jones JD
影响因子:
2.7
作者:
Cabanettes F;Klopp C
通讯作者:
Klopp C