Health-related quality of life among early-stage, non-small cell, lung cancer survivors.
Health-related quality of life among early-stage, non-small cell, lung cancer survivors.
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DOI：
10.1016/j.lungcan.2010.04.011
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发表时间：
2011-01
期刊：
影响因子：
5.3
通讯作者：
Park, Bernard J.
中科院分区：
文献类型：
--
作者：
Ostroff, Jamie S.;Krebs, Paul;Coups, Elliot J.;Burkhalter, Jack E.;Feinstein, Marc B.;Steingart, Richard M.;Logue, Amy E.;Park, Bernard J.
关于诊断和治疗早期肺癌的个人的身体和精神功能的数据有限。为了为越来越多的肺癌幸存者制定治疗后指南和有针对性的资源，需要有关长期健康相关生活质量（HQOL）的临床相关信息。目前的研究检查了肺癌幸存者的HQOL，并确定了HQOL与人口统计学，疾病和心理社会风险因素之间的关联。共有359名诊断为IA或IB期非小细胞肺癌并接受手术治疗的个体通过邮件或电话完成了治疗后调查，其中包括SF-36 v2以及人口统计学、医学、心理和身体症状指数。为了更好地了解肺癌治疗的影响，我们研究了年龄和性别调整后的HQOL差异，与人口统计学匹配的老年人样本相比，大多数有显著的吸烟史，他们参加了肺癌筛查试验。还确定了HQOL受损的风险因素。与筛查样本相比，肺癌幸存者报告的身体健康评分较低，但在心理健康状况方面没有差异。呼吸困难和抑郁情绪与HQOL损害最相关。早期肺癌幸存者可能会经历身体功能的轻度损害。他们可能会受益于管理的痛苦情绪和转介到身体活动和肺康复计划，以促进HQOL的结果。
Limited data are available about the physical and mental functioning of individuals diagnosed and treated for early stage lung cancer. To develop post-treatment guidelines and targeted resources for the growing number of lung cancer survivors, clinically relevant information about longer-term health-related quality of life (HQOL) is needed. The current study examines lung cancer survivors' HQOL and identifies associations between HQOL and demographic, disease and psychosocial risk factors. A total of 359 individuals diagnosed and surgically treated for Stage IA or IB non-small cell lung cancer completed a post-treatment survey via mail or telephone that included the SF-36v2 as well as demographic, medical, psychological and physical symptom indices. To better understand the impact of lung cancer treatment, we examined age- and gender-adjusted differences in HQOL as compared to a demographically matched sample of older adults, most with a significant smoking history, who participated in a lung cancer screening trial. Risk factors for impairments in HQOL were also identified. Compared to the screening sample, lung cancer survivors reported lower physical health scores, but did not differ in terms of mental health status. Dyspnea and distressed mood were most associated with HQOL impairments. Early stage lung cancer survivors are likely to experience mild impairment in physical functioning. They may benefit from management of distressed mood and referral to physical activity and pulmonary rehabilitation programs to promote HQOL outcomes.
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影响因子：
45.3
作者：
Kenny, Patricia M.;King, Madeleine T.;McCaughan, Brian C.
通讯作者：
McCaughan, Brian C.
影响因子：
20.4
作者：
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影响因子：
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作者：
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通讯作者：
Ståhle, E
影响因子：
9.6
作者：
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通讯作者：
VOELKER, HT