Effect of food insecurity on chronic kidney disease in lower-income Americans.
Effect of food insecurity on chronic kidney disease in lower-income Americans.
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DOI：
10.1159/000357595
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发表时间：
2014
影响因子：
4.2
通讯作者：
Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team
中科院分区：
文献类型：
--
作者：
Crews DC;Kuczmarski MF;Grubbs V;Hedgeman E;Shahinian VB;Evans MK;Zonderman AB;Burrows NR;Williams DE;Saran R;Powe NR;Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team
粮食不安全（无法获得营养充足和安全的食物）与慢性肾病（CKD）的关系尚不清楚。我们研究了在美国普通成年人和城市人口中，食物不安全是否与低收入人群中普遍存在的CKD相关。我们对2003-2008年国家健康和营养调查（NHANES）（n= 9，126）的低收入参与者进行了横断面分析;以及跨寿命多样性社区的健康老龄化（HANDLS）研究（n= 1，239）。食物不安全的定义基于问卷调查，CKD的定义是肾小球滤过率估计值降低或蛋白尿;用多变量logistic回归进行调整。在NHANES中，高、边缘和无粮食不安全组的年龄调整后CKD患病率分别为20.3%、17.6%和15.7%。调整社会人口统计学和吸烟状况的分析显示，仅在糖尿病[比值比（OR）1.67，95%置信区间（CI）1.14-2.45，与无食物不安全组相比]或高血压（OR 1.37，95% CI 1.03-1.82）的参与者中，食物不安全与CKD的更大几率相关。在HANDLS中，经年龄调整的CKD患病率分别为5.9%和4.6%（P=0.33）。食物不安全与CKD发生率增加的趋势相关（OR 1.46，95%CI 0.98-2.18），在糖尿病、高血压或肥胖亚组中没有证据表明影响改变。粮食不安全可能导致肾病的差异，特别是在糖尿病或高血压患者中，值得进一步研究。
The relation of food insecurity (inability to acquire nutritionally adequate and safe foods) and chronic kidney disease (CKD) is unknown. We examined whether food insecurity is associated with prevalent CKD among lower income individuals in both the general U.S. adult population and an urban population. We conducted cross-sectional analyses of lower income participants of the National Health and Nutrition Examination Survey (NHANES) 2003–2008 (n=9,126); and the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study (n=1,239). Food insecurity was defined based on questionnaires and CKD was defined by reduced estimated glomerular filtration rate or albuminuria; adjustment was performed with multivariable logistic regression. In NHANES, the age-adjusted prevalence of CKD was 20.3%, 17.6% and 15.7% for the high, marginal and no food insecurity groups, respectively. Analyses adjusting for sociodemographics and smoking status revealed high food insecurity to be associated with greater odds of CKD only among participants with either diabetes [odds ratio (OR) 1.67, 95% confidence interval (CI) 1.14–2.45 comparing high to no food insecurity group] or hypertension (OR 1.37, 95% CI 1.03–1.82). In HANDLS, the age-adjusted CKD prevalence was 5.9% and 4.6% for those with and without food insecurity, respectively (P=0.33). Food insecurity was associated with a trend towards greater odds of CKD (OR 1.46, 95% CI 0.98–2.18) with no evidence of effect modification across diabetes, hypertension or obesity subgroups. Food insecurity may contribute to disparities in kidney disease, especially among persons with diabetes or hypertension, and is worthy of further study.
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DOI：
10.1053/j.ajkd.2012.05.010
发表时间：
2012-11
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Crews DC;McClellan WM;Shoham DA;Gao L;Warnock DG;Judd S;Muntner P;Miller ER;Powe NR
通讯作者：
Powe NR
影响因子：
13.6
作者：
Hallan, Stein I.;Coresh, Josef;Holmen, Jostein
通讯作者：
Holmen, Jostein
影响因子：
3.2
作者：
Casagrande SS;Franco M;Gittelsohn J;Zonderman AB;Evans MK;Fanelli Kuczmarski M;Gary-Webb TL
通讯作者：
Gary-Webb TL
DOI：
10.1053/j.ajkd.2009.12.032
发表时间：
2010-06
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Crews DC;Charles RF;Evans MK;Zonderman AB;Powe NR
通讯作者：
Powe NR
DOI：
10.1097/01.asn.0000070152.11927.4a
发表时间：
2003-07-01
影响因子：
13.6
作者：
Chadban, SJ;Briganti, EM;Atkins, RC
通讯作者：
Atkins, RC