Epidemiology of Adenomyosis.

Epidemiology of Adenomyosis.
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DOI:
10.1055/s-0040-1718920
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发表时间:
2020-05
影响因子:
2.7
通讯作者:
Missmer SA
Missmer SA
中科院分区:
医学4区
文献类型:
--
作者:
Upson K;Missmer SA

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子宫腺肌症以子宫内膜腺和间质存在于子宫肌层为特征,可对女性的生活质量产生重大影响。尽管如此,对这种情况的流行病学研究远远落后于对其他非癌性生殖健康状况的研究。缺乏进展和知识部分是由于设计有效的流行病学研究的挑战,因为子宫腺肌症的诊断历史上仅限于检查子宫切除术后的子宫标本。这篇综述描述了关于这种疾病发生频率的现有数据,以及迄今为止对疾病危险因素的流行病学调查,强调了主要围绕研究样本选择的方法学和推理挑战。最后,我们对未来流行病学研究的方法提出建议,利用成像技术的进步来检测子宫腺肌症,并提供更全面的疾病发生和危险因素。
Adenomyosis, characterized by the presence of endometrial glands and stroma within the myometrium, can have a substantial impact on the quality of women’s lives. Despite this, the epidemiologic research on this condition lags considerably behind that of other non-cancerous reproductive health conditions. The lack of progress and knowledge is due in part to the challenges in designing valid epidemiologic studies, since the diagnosis of adenomyosis historically has been limited to examination of uterine specimens from hysterectomy. This review describes the available data on the frequency of this condition and the epidemiologic investigation thus far into the risk factors for disease – highlighting the methodologic and inference challenges primarily around study sample selection. We conclude with providing recommendations for approaches to future epidemiologic study that capitalize on the advancements in imaging technology to detect adenomyosis and provide a fuller picture of the occurrence and risk factors for disease.
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