The Prevalence and Specificity of Depression Diagnosis in a Clinic-Based Population of Adults With Type 2 Diabetes Mellitus.
The Prevalence and Specificity of Depression Diagnosis in a Clinic-Based Population of Adults With Type 2 Diabetes Mellitus.
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DOI：
10.1016/j.psym.2016.08.003
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发表时间：
2017-01
期刊：
影响因子：
3.4
通讯作者：
Lyketsos C
中科院分区：
文献类型：
--
作者：
Golden SH;Shah N;Naqibuddin M;Payne JL;Hill-Briggs F;Wand GS;Wang NY;Langan S;Lyketsos C
评估以临床为基础的成人2型糖尿病人群中轻度抑郁障碍(Mind)的粗略患病率。我们使用患者健康问卷-2对702名成年2型糖尿病患者的抑郁症状进行了筛查，并对52名筛查阳性和51名筛查阴性的患者进行了结构化的精神病学诊断访谈。抑郁障碍的诊断使用精神疾病诊断和统计手册IV(DSM-IV)文本修订的标准，并被归类为精神、严重抑郁障碍(MDD)或无抑郁障碍。我们估计了精神疾病和MDD的患病率，并得出了95%的CI。现在、过去和现在或过去心理的粗略患病率分别为4.3%(95%CI：0.9-9.2%)、9.6%(95%CI：3.9-15.9%)和13.9%(95%CI：7.7-21.2%)。现在、过去和现在或过去MDD的粗患率略高，分别为5.0%(95%可信区间：1.9-9.4%)、12.0%(95%可信区间：6.1-19.5%)和17.0%(95%可信区间：10.1-24.8%)。在有心理障碍(42.2%)和精神障碍(8.1%)的个体中，焦虑障碍并存的患病率很高。与那些没有抑郁障碍的人相比，有精神障碍或MDD的人的血红蛋白A1c水平没有显著差异。精神疾病在2型糖尿病患者中的流行程度与MDD相当；这两种疾病都与伴随的焦虑障碍有关。Mind不包括在DSM-5中；然而，我们的数据支持继续检查患有慢性疾病的患者的Mind。
To estimate the crude prevalence of minor depressive disorder (MinD) in a clinic-based population of adults with type 2 diabetes. We screened a clinical sample of 702 adults with type 2 diabetes for depressive symptoms using the Patient Health Questionnaire-2 and performed a structured diagnostic psychiatric interview on 52 screen-positive and a convenience sample of 51 screen-negative individuals. Depressive disorder diagnoses were made using Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) Text Revised criteria and categorized as MinD, major depressive disorder (MDD), or no depressive disorder. We estimated prevalence of MinD and MDD and derived 95% CIs. The crude prevalence of current, past, and current or past MinD was 4.3% (95% CI: 0.9–9.2%), 9.6% (95% CI: 3.9–15.9%), and 13.9% (95% CI: 7.7–21.2%), respectively. The crude prevalence of current, past, and current or past MDD was slightly higher—5.0% (95% CI: 1.9–9.4%), 12.0% (95% CI: 6.1–19.5%), and 17.0% (95% CI: 10.1–24.8%), respectively. There was a high prevalence of coexisting anxiety disorders in individuals with MinD (42.2%) and MDD (8.1%). Hemoglobin A1c levels were not significantly different in individuals with MinD or MDD compared to those without a depressive disorder. MinD is comparably prevalent to MDD in patients with type 2 diabetes; both disorders are associated with concomitant anxiety disorders. MinD is not included in the DSM-5; however, our data support continuing to examine patients with chronic medical conditions for MinD.
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