Sleep symptoms associated with intake of specific dietary nutrients.
Sleep symptoms associated with intake of specific dietary nutrients.
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DOI：
10.1111/jsr.12084
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发表时间：
2014-02
影响因子：
4.4
通讯作者：
Knutson KL
中科院分区：
文献类型：
--
作者：
Grandner MA;Jackson N;Gerstner JR;Knutson KL
睡眠症状与体重增加和心脏代谢疾病有关。饮食的潜在作用在很大程度上尚未被探索。使用 2007-2008 年 NHANES 的数据 (N=4,552) 来确定全国代表性样本中哪些营养素与睡眠症状相关。调查项目评估了入睡困难、睡眠维持困难、非恢复性睡眠和白天嗜睡。根据能量摄入、其他饮食因素、运动、体重指数和社会人口统计学对分析进行了调整。群体加权逻辑回归和向后逐步选择检查了哪些营养素与睡眠症状相关。比值比 (OR) 反映了与营养加倍相关的睡眠症状的几率差异。与入睡困难独立相关的营养素包括（按顺序）：α-胡萝卜素（OR=0.96）、硒（OR=0.80）、十二烷酸（OR=0.91）、钙（OR=0.83）和十六烷酸（OR=1.10）。与睡眠维持困难独立相关的营养素包括：盐（OR=1.19）、丁酸（0.81）、碳水化合物（OR=0.71）、十二烷酸（OR=0.90）、维生素D（OR=0.84）、番茄红素（OR=0.98）、己酸（OR=1.25）和水分（OR=1.27）。与非恢复性睡眠独立相关的营养素包括丁酸（OR=1.09）、钙（OR=0.81）、维生素C（OR=0.92）、水（OR=0.98）、水分（OR=1.41）和胆固醇（OR=1.10）。与困倦独立相关的营养素包括：水分（OR=1.20）、可可碱（OR=1.04）、钾（OR=0.70）、水（OR=0.97）。这些结果表明睡眠症状与饮食/代谢之间存在新的关联，可能解释睡眠与心脏代谢疾病之间的关联。
Sleep symptoms are associated with weight gain and cardiometabolic disease. The potential role of diet has been largely unexplored. Data from the 2007–2008 NHANES were used (N=4,552) to determine which nutrients were associated with sleep symptoms in a nationally-representative sample. Survey items assessed difficulty falling asleep, sleep maintenance difficulties, non-restorative sleep, and daytime sleepiness. Analyses were adjusted for energy intake, other dietary factors, exercise, BMI and sociodemographics. Population-weighted, logistic regression, with backwards-stepwise selection, examined which nutrients were associated with sleep symptoms. Odds ratios (ORs) reflect the difference in odds of sleep symptoms associated with a doubling in nutrient. Nutrients that were independently associated with difficulty falling asleep included (in order): Alpha-Carotene (OR=0.96), Selenium (OR=0.80), Dodecanoic Acid (OR=0.91), Calcium (OR=0.83), and Hexadecanoic Acid (OR=1.10). Nutrients that were independently associated with sleep maintenance difficulties included: Salt (OR=1.19), Butanoic Acid (0,81), Carbohydrate (OR=0.71), Dodecanoic Acid (OR=0.90), Vitamin D (OR=0.84),, Lycopene (OR=0.98), Hexanoic Acid (OR= 1.25), and Moisture (OR=1.27). Nutrients that were independently associated with non-restorative sleep included Butanoic Acid (OR=1.09), Calcium (OR=0.81), Vitamin C (OR=0.92), Water (OR=0.98), Moisture (OR= 1.41), and Cholesterol (OR= 1.10). Nutrients that were independently associated with sleepiness included: Moisture (OR=1.20), Theobromine (OR=1.04), Potassium (OR= 0.70), Water (OR=0.97). These results suggest novel associations between sleep symptoms and diet/metabolism, potentially explaining associations between sleep and cardiometabolic diseases.
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影响因子：
6.9
作者：
Alexander, Katharine E.;Ventura, Emily E.;Davis, Jaimie N.
通讯作者：
Davis, Jaimie N.
影响因子：
5.4
作者：
Grandner, Michael A.;Jackson, Nicholas;Gerstner, Jason R.;Knutson, Kristen L.
通讯作者：
Knutson, Kristen L.
DOI：
10.1073/pnas.1216951110
发表时间：
2013-04-02
影响因子：
11.1
作者：
Markwald, Rachel R.;Melanson, Edward L.;Wright, Kenneth P., Jr.
通讯作者：
Wright, Kenneth P., Jr.
影响因子：
9.6
作者：
Calvin, Andrew D.;Carter, Rickey E.;Somers, Virend K.
通讯作者：
Somers, Virend K.
影响因子：
4.2
作者：
de Roos, NM;Schouten, EG;Katan, MB
通讯作者：
Katan, MB