Comparison by magnetic resonance phase contrast imaging of pulse-wave velocity in patients with single ventricle who have reconstructed aortas versus those without.
Comparison by magnetic resonance phase contrast imaging of pulse-wave velocity in patients with single ventricle who have reconstructed aortas versus those without.
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DOI：
10.1016/j.amjcard.2014.09.032
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发表时间：
2014-12-15
影响因子：
2.8
通讯作者：
Whitehead, Kevin K.
中科院分区：
文献类型：
--
作者：
Fogel, Mark A.;Li, Christine;Nicolson, Susan C.;Spray, Thomas L.;Gaynor, J. William;Fuller, Stephanie;Keller, Marc S.;Harris, Matthew A.;Yoganathan, Ajit P.;Whitehead, Kevin K.
Pulse wave velocity (PWV), a measure of arterial stiffness, is a known independent risk factor for cardiovascular events. Single ventricle patients who undergo aortic to pulmonary anastomosis (recon) have non-compliant patch material inserted into the neo-aorta, possibly increasing vessel stiffness and afterload. The purpose of this study is to determine if PWV differed in single ventricle patients who did and did not undergo aortic reconstruction (no-recon). We retrospectively reviewed cardiac magnetic resonance anatomic, cine and phase contrast evaluations in the ascending (AAo) and descending aorta (DAo) at the level of the diaphragm data from 126 single ventricle patients (8.6±8.0 years) from January 2012 to May, 2013. Significance = P<0.05. Seventy-five underwent recon and 51 did not. PWV in recon were significantly higher than in no-recon (3.9±0.9 m/s vs 3.2±1.0 m/s, P=0.008); in recon, patients > 13 years had a higher PWV than those < 7 years (4.5±0.6 vs 3.5±0.7 m/s, P=0.004). DAo distensibility was similar between both groups. There was no difference in age, body surface area or cardiac index between recon and no-recon. No correlations between various hemodynamic and ventricular function parameters with PWV were noted. In conclusion, PWV in recon is higher than in no-recon with similar DAo distensibility implicating the aortic reconstruction as a possible cause of increased afterload; older recon have stiffer aortas than younger ones possibly imposing an additional cardiovascular risk in the future. Other biomaterials may potentially moderate PWV if clinical outcome is adversely affected.
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DOI：
10.1186/1532-429x-14-77
发表时间：
2012-11-14
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Voges I;Jerosch-Herold M;Hedderich J;Pardun E;Hart C;Gabbert DD;Hansen JH;Petko C;Kramer HH;Rickers C
通讯作者：
Rickers C
DOI：
10.1016/j.jtcvs.2012.08.028
发表时间：
2012-12-01
影响因子：
6
作者：
Biglino, Giovanni;Schievano, Silvia;Giardini, Alessandro
通讯作者：
Giardini, Alessandro
DOI：
10.1161/circimaging.108.832113
发表时间：
2009-09
期刊：
Circulation. Cardiovascular imaging
影响因子：
--
作者：
Whitehead KK;Gillespie MJ;Harris MA;Fogel MA;Rome JJ
通讯作者：
Rome JJ
影响因子：
37.8
作者：
Voges, Inga;Jerosch-Herold, Michael;Rickers, Carsten
通讯作者：
Rickers, Carsten
DOI：
10.1098/rspb.1922.0022
发表时间：
1922-04-01
期刊：
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-CONTAINING PAPERS OF A BIOLOGICAL CHARACTER
影响因子：
--
作者：
Bramwell, JC
通讯作者：
Bramwell, JC