Vinyl Chloride Monomer (VCM) Induces High Occurrence of Neural Tube Defects in Embryonic Mouse Brain During Neurulation

Vinyl Chloride Monomer (VCM) Induces High Occurrence of Neural Tube Defects in Embryonic Mouse Brain During Neurulation
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氯乙烯单体(VCM)在神经形成过程中诱导胚胎小鼠大脑神经管缺陷的高发生率

DOI:
10.1007/s10571-014-0049-6
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发表时间:
2014-03
影响因子:
4
通讯作者:
Li, Hongli
Li, Hongli
中科院分区:
医学3区
文献类型:
--
作者:
Zhao, Xianxian;Zhao, Baixiong;Liu, Yunlai;Li, Hongli

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本研究旨在探讨氯乙烯单体(VCM)对胚胎的直接致畸作用,特别是对神经系统早期发育的毒性作用及其机制。胚胎第6.5天(E6.5)的妊娠小鼠
The aim of this study was to explore the direct embryonic teratogenicity of vinyl chloride monomer (VCM), especially the toxic effects on the early development of the nervous system and its underlying mechanisms. Pregnant mice at embryonic day 6.5 (E6.5)
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