Iterative image reconstruction for cerebral perfusion CT using a pre-contrast scan induced edge-preserving prior.
Iterative image reconstruction for cerebral perfusion CT using a pre-contrast scan induced edge-preserving prior.
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使用预对比扫描诱导边缘保留先验的脑灌注 CT 迭代图像重建
DOI:
10.1088/0031-9155/57/22/7519
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发表时间:
2012-11-21
影响因子:
3.5
通讯作者:
Chen W
中科院分区:
文献类型:
--
作者:
Ma J;Zhang H;Gao Y;Huang J;Liang Z;Feng Q;Chen W
Cerebral perfusion X-ray computed tomography (PCT) imaging, which detects and characterizes the ischemic penumbra, and assesses blood-brain barrier permeability with acute stroke or chronic cerebrovascular diseases, has been developed extensively over the past decades. However, due to its sequential scan protocol, the associated radiation dose has raised significant concerns to patients. Therefore, in this study we developed an iterative image reconstruction algorithm based on the maximum a posterior (MAP) principle to yield a clinically acceptable cerebral PCT image with lower milliampere seconds (mAs). To preserve the edges of the reconstructed image, an edge-preserving prior was designed using a normal-dose pre-contrast unenhanced scan. For simplicity, the present algorithm was termed as “MAP-ndiNLM”. Evaluations with the digital phantom and the simulated low-dose clinical brain PCT datasets clearly demonstrate that the MAP-ndiNLM method can achieve more significant gains than the existing FBP and MAP-Huber algorithms with better image noise reduction, low-contrast object detection and resolution preservation. More importantly, the MAP-ndiNLM method can yield more accurate kinetic enhanced details and diagnostic hemodynamic parameter maps than the MAP-Huber method.
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影响因子:
3.5
作者:
Badea CT;Johnston SM;Qi Y;Johnson GA
通讯作者:
Johnson GA
影响因子:
10.6
作者:
Han X;Bian J;Eaker DR;Kline TL;Sidky EY;Ritman EL;Pan X
通讯作者:
Pan X
影响因子:
19.7
作者:
Koenig, M;Klotz, E;Heuser, L
通讯作者:
Heuser, L
影响因子:
5.1
作者:
Mignotte, Max
通讯作者:
Mignotte, Max
影响因子:
19.7
作者:
Fleischmann, D;Rubin, GD;Hittmair, K
通讯作者:
Hittmair, K