Efficacy of a group-based multimedia HIV prevention intervention for drug-involved women under community supervision: project WORTH.
Efficacy of a group-based multimedia HIV prevention intervention for drug-involved women under community supervision: project WORTH.
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DOI：
10.1371/journal.pone.0111528
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Witte S
中科院分区：
文献类型：
--
作者：
El-Bassel N;Gilbert L;Goddard-Eckrich D;Chang M;Wu E;Hunt T;Epperson M;Shaw SA;Rowe J;Almonte M;Witte S
这项研究旨在解决需要在刑事司法社区监督下对吸毒妇女采取基于证据的艾滋病毒/性传播感染预防办法。我们在社区监督下，在吸毒妇女中测试了基于小组的传统和多媒体艾滋病毒/性传播感染预防干预措施（项目价值：妇女在健康之路上）的有效性。我们从社区监督机构招募了306名妇女，随机接受以下两种治疗：（1）四次传统的基于小组的艾滋病毒/性传播感染预防干预（2）一个四次会议的多媒体小组艾滋病毒/性传播感染预防干预，内容与传统的WORTH相同，但以计算机化的形式提供;或（3）作为注意力控制条件的四次基于小组的健康促进干预。该研究探讨了传统或多媒体WORTH干预是否比健康促进更有效地降低风险;以及多媒体WORTH是否比传统WORTH更有效地降低风险。在干预后的12个月内评估主要结果，包括无保护性行为的数量、有保护性行为的比例和避孕套的持续使用。在基线时，77%的参与者报告了无保护的阴道或肛交（n = 237），63%（n = 194）有多个性伴侣。 分配到传统或多媒体WORTH组的女性比分配到对照组的女性更有可能报告保护性行为的比例增加（β = 0.10; 95% CI = 0.02-0.18）和无保护性行为的数量减少（IRR = 0.72; 95% CI = 0.57-0.90）。 传统和多媒体的WORTH在增加安全套使用和高参与率方面的良好效果表明，可以扩大WORTH的规模，以解决刑事司法系统中吸毒妇女中艾滋病毒/性传播感染集中流行的问题。ClinicalTrials.gov www.example.com
This study is designed to address the need for evidence-based HIV/STI prevention approaches for drug-involved women under criminal justice community supervision. We tested the efficacy of a group-based traditional and multimedia HIV/STI prevention intervention (Project WORTH: Women on the Road to Health) among drug-involved women under community supervision. We randomized 306 women recruited from community supervision settings to receive either: (1) a four-session traditional group-based HIV/STI prevention intervention (traditional WORTH); (2) a four-session multimedia group-based HIV/STI prevention intervention that covered the same content as traditional WORTH but was delivered in a computerized format; or (3) a four-session group-based Wellness Promotion intervention that served as an attention control condition. The study examined whether the traditional or multimedia WORTH intervention was more efficacious in reducing risks when compared to Wellness Promotion; and whether multimedia WORTH was more efficacious in reducing risks when compared to traditional WORTH. Primary outcomes were assessed over the 12-month post-intervention period and included the number of unprotected sex acts, the proportion of protected sex acts, and consistent condom use. At baseline, 77% of participants reported unprotected vaginal or anal sex (n = 237) and 63% (n = 194) had multiple sex partners. Women assigned to traditional or multimedia WORTH were significantly more likely than women assigned to the control condition to report an increase in the proportion of protected sex acts (β = 0.10; 95% CI = 0.02–0.18) and a decrease in the number of unprotected sex acts (IRR = 0.72; 95% CI = 0.57–0.90). The promising effects of traditional and multimedia WORTH on increasing condom use and high participation rates suggest that WORTH may be scaled up to redress the concentrated epidemics of HIV/STIs among drug-involved women in the criminal justice system. ClinicalTrials.gov NCT01784809
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