Comparison of blue light-filtering IOLs and UV light-filtering IOLs for cataract surgery: a meta-analysis.
Comparison of blue light-filtering IOLs and UV light-filtering IOLs for cataract surgery: a meta-analysis.
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DOI：
10.1371/journal.pone.0033013
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Zhao NQ
中科院分区：
文献类型：
--
作者：
Zhu XF;Zou HD;Yu YF;Sun Q;Zhao NQ
已经进行了许多已发表的随机对照试验，以评价白内障超声乳化手术后蓝光过滤人工晶状体（IOL）和紫外线过滤人工晶状体（IOL）的视觉性能。然而，结果并不总是一致的。因此，我们进行了一项荟萃分析，以比较蓝光过滤IOL与紫外线过滤IOL在白内障手术中的有效性。使用基于Web的搜索引擎对PubMed、Embase、科克伦图书馆和中国生物医学文献数据库进行全面检索。系统性综述纳入了15项试验（1690只眼），15项研究中的11项纳入了本荟萃分析。结果显示，蓝光过滤IOL和紫外线过滤IOL之间的术后平均最佳矫正视力、对比敏感度、总体色觉或明视光条件下的蓝光光谱无显著差异[WMD = −0.01，95%CI（−0.03，0.01），P = 0.46; WMD = 0.07，95%CI（−0.04，0.19），P = 0.20; SMD = 0.14，95%CI（−0.33，0.60），P = 0.566; SMD = 0.20，95%CI（−0.04，0.43），P = 0.099]。 然而，在中间光条件下，使用蓝光过滤IOL的色觉在蓝光光谱中显著降低[SMD = 0.74，95%CI（0.29，1.18），P = 0.001]。 该荟萃分析表明，在白内障手术后，使用蓝光过滤IOL的术后视觉表现与使用紫外线过滤IOL的术后视觉表现大致相同，但在中间光条件下，使用蓝光过滤IOL的色觉在蓝光光谱方面表现出一定程度的损害。
A number of published randomized controlled trials have been conducted to evaluate visual performance of blue light-filtering intraocular lenses (IOL) and UV light-filtering intraocular lenses (IOL) after cataract phacoemulsification surgery. However, results have not always been consistent. Therefore, we carried out a meta-analysis to compare the effectiveness of blue light-filtering IOLs versus UV light-filtering IOLs in cataract surgery. Comprehensive searches of PubMed, Embase, Cochrane Library and the Chinese BioMedical literature databases were performed using web-based search engines. Fifteen trials (1690 eyes) were included for systematic review, and 11 of 15 studies were included in this meta-analysis. The results showed that there were no significant differences in postoperative mean best corrected visual acuity, contrast sensitivity, overall color vision, or in the blue light spectrum under photopic light conditions between blue light-filtering IOLs and UV light-filtering IOLs [WMD = −0.01, 95%CI (−0.03, 0.01), P = 0.46; WMD = 0.07, 95%CI (−0.04, 0.19), P = 0.20; SMD = 0.14, 95%CI (−0.33, 0.60), P = 0.566; SMD = 0.20, 95%CI (−0.04, 0.43), P = 0.099]. However, color vision with blue light-filtering IOLs was significantly reduced in the blue light spectrum under mesopic light conditions [SMD = 0.74, 95%CI (0.29, 1.18), P = 0.001]. This meta-analysis demonstrates that postoperative visual performance with blue light-filtering IOLs is approximately equal to that of UV light-filtering IOLs after cataract surgery, but color vision with blue light-filtering IOLs demonstrated some compromise in the blue light spectrum under mesopic light conditions.
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