Cardiovascular reactivity as a mechanism linking child trauma to adolescent psychopathology.
Cardiovascular reactivity as a mechanism linking child trauma to adolescent psychopathology.
复制标题
心血管反应性作为将儿童创伤与青少年心理病理学联系起来的机制。
DOI：
10.1016/j.biopsycho.2016.08.007
复制
发表时间：
2016-10
影响因子：
2.6
通讯作者：
Riese, Harriette
中科院分区：
文献类型：
--
作者：
Heleniak, Charlotte;McLaughlin, Katie A.;Ormel, Johan;Riese, Harriette
关键词：
对压力的生理反应的改变被认为是将不良童年环境经历与内化和外化精神病理学联系起来的核心机制。童年创伤暴露可能会影响生理反应的压力在不同的方式从其他形式的童年逆境。本研究应用了一个新的理论模型来研究儿童创伤对心血管应激反应的影响-挑战和威胁的生物心理社会模型。该模型表明，对压力的无效心血管反应-与挑战概况相反的威胁-的特征在于钝心输出量（CO）反应性和增加的血管阻力。我们在追踪青少年个体生活调查（TRAILS）中研究了儿童期创伤暴露是否预测了心血管反应性威胁特征的指标，以及这种模式是否与488名青少年（M = 16.17岁，49.2%为男孩）的人群代表性样本中的青少年精神病理学相关。暴露于创伤与内化和外化症状以及与威胁特征一致的心血管反应性模式相关，包括社会应激任务期间的钝化CO反应性。钝性CO反应，反过来，正相关的外化，但不内化症状和介导的创伤和外化精神病理学之间的联系。这些联系没有因性别而异。挑战和威胁的生物心理社会模型提供了一个新的理论框架，了解中断的生理反应，以压力以下的童年创伤暴露，揭示了一个潜在的途径，这种暴露与外化问题的青少年。
Alterations in physiological reactivity to stress are argued to be central mechanisms linking adverse childhood environmental experiences to internalizing and externalizing psychopathology. Childhood trauma exposure may influence physiological reactivity to stress in distinct ways from other forms of childhood adversity. This study applied a novel theoretical model to investigate the impact of childhood trauma on cardiovascular stress reactivity – the biopsychosocial model of challenge and threat. This model suggests that inefficient cardiovascular responses to stress – a threat as opposed to challenge profile – are characterized by blunted cardiac output (CO) reactivity and increased vascular resistance. We examined whether childhood trauma exposure predicted an indicator of the threat profile of cardiovascular reactivity and whether such a pattern was associated with adolescent psychopathology in a population-representative sample of 488 adolescents (M = 16.17 years old, 49.2% boys) in the TRacking Adolescents’ Individual Lives Survey (TRAILS). Exposure to trauma was associated with both internalizing and externalizing symptoms and a pattern of cardiovascular reactivity consistent with the threat profile, including blunted CO reactivity during a social stress task. Blunted CO reactivity, in turn, was positively associated with externalizing, but not internalizing symptoms and mediated the link between trauma and externalizing psychopathology. None of these associations varied by gender. The biopsychosocial model of challenge and threat provides a novel theoretical framework for understanding disruptions in physiological reactivity to stress following childhood trauma exposure, revealing a potential pathway linking such exposure with externalizing problems in adolescents.
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影响因子：
3.3
作者：
Ellis, BJ;Essex, MJ;Boyce, WT
通讯作者：
Boyce, WT
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56.9
作者：
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通讯作者：
PETTIT, GS