Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses.
Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses.
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DOI：
10.1016/j.neubiorev.2022.104857
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发表时间：
2022-11
影响因子：
8.2
通讯作者：
Solmi, Marco
中科院分区：
文献类型：
--
作者：
Monteleone, Alessio Maria;Pellegrino, Francesca;Croatto, Giovanni;Carfagno, Marco;Hilbert, Anja;Treasure, Janet;Wade, Tracey;Bulik, Cynthia M.;Zipfel, Stephan;Hay, Phillipa;Schmidt, Ulrike;Castellini, Giovanni;Favaro, Angela;Fernandez-Aranda, Fernando;Shin, Jae Il;Voderholzer, Ulrich;Ricca, Valdo;Moretti, Davide;Busatta, Daniele;Abbate-Daga, Giovanni;Ciullini, Filippo;Cascino, Giammarco;Monaco, Francesco;Correll, Christoph U.;Solmi, Marco
关键词：
上午，蒙特莱昂，F.佩莱格里诺湾克罗阿托湾Carfagno，A.希尔伯特，J. Treasure，T.韦德角，澳-地Bulik，S. Zipfel，P. Hay，U.施密特，G. Castellini，A. Favaro，F. Fernando-Aranda，J. Il Shin，U. Voderholzer，V. Ricca，D. Moretti，D.布萨塔湾Abbate-Daga，F.丘利尼湾Cascino，F.摩纳哥，C.U. Correll和M.索尔米饮食失调的治疗：荟萃分析和网络荟萃分析的系统性荟萃评价。NEUROSCI BIOSDE V修订版21（1）XXX-XXX，2022年。-进食障碍（ED）的治疗效果是适度的，指南不同。我们总结了ED随机对照试验（RCT）的（网络）荟萃分析（N）MA的结果/质量。截至2020年12月15日，使用PubMed/PsycINFO/科克伦数据库中的（厌食症或贪食症或进食障碍）和（荟萃分析 *）进行系统性荟萃综述（RCT、艾德、活性/非活性对照的（N）MA）。在治疗结束和随访时总结标准化平均差异、比值/风险比与对照组。在成人/青少年神经性厌食症（AN）和青少年神经性贪食症（BN）中，涉及家庭的干预（以家庭为基础的治疗，FBT）优于主动控制。在成人BN患者中，个体认知行为疗法（CBT）-艾德与活性对照相比具有最广泛的疗效;抗抑郁药也优于活性药物。在混合年龄组的暴食症（BED），心理治疗，利右苯丙胺优于积极控制。抗抑郁药，兴奋剂优于安慰剂，尽管可接受性较低，CBT-ED与等待名单/无治疗。以家庭为基础的治疗是有效的AN和BN（青少年）。CBT-ED对BN（成人）的疗效最大，其次是抗抑郁药，以及BED（混合）的心理治疗。药物在BED（成人）中具有短期疗效。
MONTELEONE, A.M., F. Pellegrino, G. Croatto, M. Carfagno, A. Hilbert, J. Treasure, T. Wade, C. Bulik, S. Zipfel, P. Hay, U. Schmidt, G. Castellini, A. Favaro, F. Fernandez-Aranda, J. Il Shin, U. Voderholzer, V. Ricca, D. Moretti, D. Busatta, G. Abbate-Daga, F. Ciullini, G. Cascino, F. Monaco, C.U. Correll and M. Solmi. Treatment of Eating Disorders: a systematic meta-review of meta-analyses and network meta-analyses. NEUROSCI BIOBEHAV REV 21(1) XXX-XXX, 2022.- Treatment efficacy for eating disorders (EDs) is modest and guidelines differ. We summarized findings/quality of (network) meta-analyses (N)MA of randomized controlled trials (RCTs) in EDs. Systematic meta-review ((N)MA of RCTs, ED, active/inactive control), using (anorexia or bulimia or eating disorder) AND (meta-analy*) in PubMed/PsycINFO/Cochrane database up to December 15th, 2020. Standardized mean difference, odds/risk ratio vs control were summarized at end of treatment and follow-up. Interventions involving family (family-based therapy, FBT) outperformed active control in adults/adolescents with anorexia nervosa (AN), and in adolescents with bulimia nervosa (BN). In adults with BN, individual cognitive behavioural therapy (CBT)-ED had the broadest efficacy versus active control; also, antidepressants outperformed active. In mixed age groups with binge-eating disorder (BED), psychotherapy, and lisdexamfetamine outperformed active control. Antidepressants, stimulants outperformed placebo, despite lower acceptability, as did CBT-ED versus waitlist/no treatment. Family-based therapy is effective in AN and BN (adolescents). CBT-ED has the largest efficacy in BN (adults), followed by antidepressants, as well as psychotherapy in BED (mixed). Medications have short-term efficacy in BED (adults).
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