Role of vitamin D in adults requiring nutrition support.
Role of vitamin D in adults requiring nutrition support.
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DOI：
10.1177/0148607109349061
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发表时间：
2010-01
期刊：
影响因子：
--
通讯作者：
Saltzman E
中科院分区：
文献类型：
--
作者：
Pittas AG;Laskowski U;Kos L;Saltzman E
The major and most well known function of vitamin D is to maintain calcium and phosphorus homeostasis and promote bone mineralization. However, recent evidence suggests that vitamin D may also be important for a variety of non-skeletal outcomes. The review synthesizes the available evidence for the role of vitamin D in skeletal health as well as its novel roles in medical conditions such as muscle function, falls, immunity, glucose homeostasis and cardiovascular diseases. It reviews methods for assessing vitamin D status and it suggests strategies to restore vitamin D status in patients requiring enteral or parenteral nutrition who are at particularly high risk of hypovitaminosis D. Screening for hypovitaminosis D with plasma total 25(OH)D should be a routine part of the care of the patient requiring enteral or parenteral nutrition. Restoration of optimal vitamin D status with high dose supplemental vitamin D is required in most cases, while exposure to sunlight or an ultraviolet B radiation-emitting device is most effective in patients with severe malabsorption or those requiring chronic parenteral therapy. Given the emerging role of vitamin D for a variety of acute and chronic conditions, the optimal vitamin D status in acutely ill patients as well as in patients requiring long-term nutrition therapy warrants further investigation.
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影响因子：
6.2
作者：
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通讯作者：
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影响因子：
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DOI：
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发表时间：
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作者：
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