Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa.
Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa.
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DOI：
10.1126/science.abn4947
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发表时间：
2022-05-06
期刊：
影响因子：
--
通讯作者：
Moultrie H
中科院分区：
文献类型：
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作者：
Pulliam JRC;van Schalkwyk C;Govender N;von Gottberg A;Cohen C;Groome MJ;Dushoff J;Mlisana K;Moultrie H
在这里，我们提供了两种方法来监测常规监测数据中的再感染趋势，以确定再感染风险变化的特征，并将这些方法应用于迄今为止南非SARS-CoV-2流行的数据。虽然我们没有发现与Beta （B.1.351）或Delta （B.1.617.2）变异循环相关的再感染风险增加的证据，但我们发现了明确的人群水平证据，表明南非先前感染的个体中存在Omicron （B.1.1.529）变异的免疫逃避。在前三波感染中发现的个人在2021年11月1日至2022年1月31日期间再次感染，并且自2021年11月中旬以来发生第三次感染的风险有所增加。
Here, we provide two methods for monitoring reinfection trends in routine surveillance data to identify signatures of changes in reinfection risk and apply these approaches to data from South Africa’s SARS-CoV-2 epidemic to date. While we found no evidence of increased reinfection risk associated with circulation of Beta (B.1.351) or Delta (B.1.617.2) variants, we find clear, population-level evidence to suggest immune evasion by the Omicron (B.1.1.529) variant in previously infected individuals in South Africa. Reinfections occurring between 01 November 2021 and 31 January 2022 were detected in individuals infected in all three previous waves, and there has been an increase in the risk of having a third infection since mid-November 2021.
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影响因子：
64.5
作者：
Liu C;Ginn HM;Dejnirattisai W;Supasa P;Wang B;Tuekprakhon A;Nutalai R;Zhou D;Mentzer AJ;Zhao Y;Duyvesteyn HME;López-Camacho C;Slon-Campos J;Walter TS;Skelly D;Johnson SA;Ritter TG;Mason C;Costa Clemens SA;Gomes Naveca F;Nascimento V;Nascimento F;Fernandes da Costa C;Resende PC;Pauvolid-Correa A;Siqueira MM;Dold C;Temperton N;Dong T;Pollard AJ;Knight JC;Crook D;Lambe T;Clutterbuck E;Bibi S;Flaxman A;Bittaye M;Belij-Rammerstorfer S;Gilbert SC;Malik T;Carroll MW;Klenerman P;Barnes E;Dunachie SJ;Baillie V;Serafin N;Ditse Z;Da Silva K;Paterson NG;Williams MA;Hall DR;Madhi S;Nunes MC;Goulder P;Fry EE;Mongkolsapaya J;Ren J;Stuart DI;Screaton GR
通讯作者：
Screaton GR
影响因子：
64.8
作者：
Planas, Delphine;Veyer, David;Schwartz, Olivier
通讯作者：
Schwartz, Olivier
影响因子：
64.8
作者：
Viana R;Moyo S;Amoako DG;Tegally H;Scheepers C;Althaus CL;Anyaneji UJ;Bester PA;Boni MF;Chand M;Choga WT;Colquhoun R;Davids M;Deforche K;Doolabh D;du Plessis L;Engelbrecht S;Everatt J;Giandhari J;Giovanetti M;Hardie D;Hill V;Hsiao NY;Iranzadeh A;Ismail A;Joseph C;Joseph R;Koopile L;Kosakovsky Pond SL;Kraemer MUG;Kuate-Lere L;Laguda-Akingba O;Lesetedi-Mafoko O;Lessells RJ;Lockman S;Lucaci AG;Maharaj A;Mahlangu B;Maponga T;Mahlakwane K;Makatini Z;Marais G;Maruapula D;Masupu K;Matshaba M;Mayaphi S;Mbhele N;Mbulawa MB;Mendes A;Mlisana K;Mnguni A;Mohale T;Moir M;Moruisi K;Mosepele M;Motsatsi G;Motswaledi MS;Mphoyakgosi T;Msomi N;Mwangi PN;Naidoo Y;Ntuli N;Nyaga M;Olubayo L;Pillay S;Radibe B;Ramphal Y;Ramphal U;San JE;Scott L;Shapiro R;Singh L;Smith-Lawrence P;Stevens W;Strydom A;Subramoney K;Tebeila N;Tshiabuila D;Tsui J;van Wyk S;Weaver S;Wibmer CK;Wilkinson E;Wolter N;Zarebski AE;Zuze B;Goedhals D;Preiser W;Treurnicht F;Venter M;Williamson C;Pybus OG;Bhiman J;Glass A;Martin DP;Rambaut A;Gaseitsiwe S;von Gottberg A;de Oliveira T
通讯作者：
de Oliveira T
DOI：
10.1016/s0140-6736(21)00675-9
发表时间：
2021-04-17
期刊：
Lancet (London, England)
影响因子：
--
作者：
Hall VJ;Foulkes S;Charlett A;Atti A;Monk EJM;Simmons R;Wellington E;Cole MJ;Saei A;Oguti B;Munro K;Wallace S;Kirwan PD;Shrotri M;Vusirikala A;Rokadiya S;Kall M;Zambon M;Ramsay M;Brooks T;Brown CS;Chand MA;Hopkins S;SIREN Study Group
通讯作者：
SIREN Study Group
影响因子：
64.8
作者：
通讯作者：
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