Toxoplasmosis: A history of clinical observations.

Toxoplasmosis: A history of clinical observations.
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DOI:
10.1016/j.ijpara.2009.02.004
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发表时间:
2009-07-01
影响因子:
4
通讯作者:
Dubey JP
Dubey JP
中科院分区:
医学2区
文献类型:
--
作者:
Weiss LM;Dubey JP

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刚地弓形虫最初在突尼斯被描述为存在于刚地(Ctenodoactylus gundi)的组织中,在巴西被描述为存在于兔子的组织中,至今已有100年的历史。弓形虫是一种普遍存在的温血动物顶复门寄生虫,可引起多种临床综合征,包括脑炎、脉络膜视网膜炎、先天性感染和新生儿死亡。在描述T. Nicolle和Manceaux报道了一例儿童弓形虫病致死病例。1939年,Wolf、Cowen和Paige首先确定了T.弓形虫是人类疾病的一个原因。本文就弓形虫感染的临床表现作一综述。弓形虫和这些表现的发现历史。
It has been 100 years since Toxoplasma gondii was initially described in Tunis by in the tissues of the gundi (Ctenodoactylus gundi) and in Brazil by in the tissues of a rabbit. Toxoplasma gondii is a ubiquitous, Apicomplexan parasite of warm-blooded animals that can cause several clinical syndromes including encephalitis, chorioretinitis, congenital infection and neonatal mortality. Fifteen years after the description of T. gondii by Nicolle and Manceaux a fatal case of toxoplasmosis in a child was reported by Janků. In 1939 Wolf, Cowen and Paige were the first to conclusively identify T. gondii as a cause of human disease. This review examines the clinical manifestations of infection with T. gondii and the history of the discovery of these manifestations.
DOI: 10.1056/nejm198802043180502
发表时间: 1988-02-04
影响因子: 158.5
作者:
DAFFOS, F;FORESTIER, F;COX, WL
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