The Inner and Outer Qualities of Extracellular Vesicles for Translational Purposes in Breast Cancer.
The Inner and Outer Qualities of Extracellular Vesicles for Translational Purposes in Breast Cancer.
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DOI：
10.3389/fimmu.2018.00584
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发表时间：
2018
影响因子：
7.3
通讯作者：
Rebmann V
中科院分区：
文献类型：
--
作者：
Schwich E;Rebmann V
Breast cancer (BC) is the second most common cause of cancer mortality of women worldwide. BC is a systemic disease with a highly heterogeneous course of disease. Therefore, prognostic and diagnostic biomarkers are required to improve the clinical risk management. Cancer-derived or cancer-associated extracellular vesicles (EVs) procured from the bloodstream of BC patients offer a novel platform for the qualitative and quantitative screening and establishment of biomarkers. Here, we focus on common aspects of EVs, on the function of BC-derived EVs and their translational potential considering the EV abundancy, intravesicular as well as outer membrane-anchored composition and current challenges of implementation in clinical practice.
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影响因子：
7.3
作者：
Andreu Z;Yáñez-Mó M
通讯作者：
Yáñez-Mó M
影响因子：
3.3
作者：
Griffiths SG;Cormier MT;Clayton A;Doucette AA
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Doucette AA
影响因子：
4.6
作者：
Cappello, Francesco;Logozzi, Mariantonia;Fais, Stefano
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Fais, Stefano
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11.2
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Di Vizio D;Kim J;Hager MH;Morello M;Yang W;Lafargue CJ;True LD;Rubin MA;Adam RM;Beroukhim R;Demichelis F;Freeman MR
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Freeman MR
影响因子：
50.3
作者：
Becker A;Thakur BK;Weiss JM;Kim HS;Peinado H;Lyden D
通讯作者：
Lyden D