A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy.
A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy.
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DOI：
10.1186/s13014-014-0237-z
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发表时间：
2014-11-04
期刊：
影响因子：
--
通讯作者：
Miyatake S
中科院分区：
文献类型：
--
作者：
Futamura G;Kawabata S;Siba H;Kuroiwa T;Suzuki M;Kondo N;Ono K;Sakurai Y;Tanaka M;Todo T;Miyatake S
我们治疗了一个54岁的日本女性复发性放射诱导的骨肉瘤从左枕骨头骨，反应器为基础的硼中子俘获治疗（BNCT）。她的肿瘤生长迅速，皮下和硬膜外扩展。她最终因小脑共济失调而无法行走。肿瘤是不可手术和放射抵抗。BNCT显示了显著的初始治疗效果：皮下/硬膜外肿瘤缩小，除脱发外无头皮辐射损伤，患者在BNCT后仅3周即可行走。BNCT似乎是一个安全和非常有效的方式在管理放射性诱导的骨肉瘤，不适合手术和其他治疗方式。
We treated a 54-year-old Japanese female with a recurrent radiation-induced osteosarcoma arising from left occipital skull, by reactor-based boron neutron capture therapy (BNCT). Her tumor grew rapidly with subcutaneous and epidural extension. She eventually could not walk because of cerebellar ataxia. The tumor was inoperable and radioresistant. BNCT showed a marked initial therapeutic effect: the subcutaneous/epidural tumor reduced without radiation damage of the scalp except hair loss and the patient could walk again only 3 weeks after BNCT. BNCT seems to be a safe and very effective modality in the management of radiation-induced osteosarcomas that are not eligible for operation and other treatment modalities.
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影响因子：
3.9
作者：
Kawabata S;Yang W;Barth RF;Wu G;Huo T;Binns PJ;Riley KJ;Ongayi O;Gottumukkala V;Vicente MG
通讯作者：
Vicente MG
影响因子：
4.1
作者：
Miyatake, SI;Kawabata, S;Ono, K
通讯作者：
Ono, K
DOI：
10.1016/s0360-3016(99)00279-5
发表时间：
1999-11-01
影响因子：
7
作者：
Murray, EM;Werner, D;Taylor, DA
通讯作者：
Taylor, DA
影响因子：
1.6
作者：
Bortolussi, Silva;Ciani, Laura;Altieri, Saverio
通讯作者：
Altieri, Saverio
影响因子：
6.2
作者：
Patel, Akash J.;Rao, Vikas Y.;DeMonte, Franco
通讯作者：
DeMonte, Franco