Central quadrant procurement of radical prostatectomy specimens.

Central quadrant procurement of radical prostatectomy specimens.
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DOI:
10.1002/pros.20925
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发表时间:
2009-05-15
期刊:
影响因子:
2.8
通讯作者:
Mohler, James L.
Mohler, James L.
中科院分区:
医学3区
文献类型:
--
作者:
Morrison, Carl;Cheney, Richard;Johnson, Candace S.;Smith, Gary;Mohler, James L.

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获得克级的高质量新鲜或冷冻前列腺组织可以促进前列腺癌的研究。由于无法在新鲜前列腺的切割切片上有效识别前列腺癌,许多病理学部门进行整个器官处理,排除前列腺组织的获取。一些站点随机获取组织,而另一些站点则执行难以复制的专门程序。这两种类型的采购都没有一致地导致从每个前列腺采购的组织的克数,其中产生与癌症相对应的组织的样本百分比很高。在这项研究中,我们提出了一种简化的前列腺组织获取模型,该模型对格里森分级、肿瘤分期或边缘状态没有影响,需要最少的专门处理,并从每个根治性前列腺切除术标本中获得克量的新鲜组织,并具有高百分比的癌组织产量。
Obtaining high quality fresh or frozen prostate tissue in gram amounts promotes the research of prostate cancer. Due to the inability to effectively recognize prostate cancer upon the cut section of a fresh prostate many pathology departments perform whole organ processing precluding the procurement of prostate tissue. Some sites randomly procure tissue, while others perform specialized procedures that can be difficult to duplicate. Neither of these types of procurement consistently results in gram quantities of tissue procured from each prostate with a high percentage of samples yielding tissue corresponding to cancer. In this study, we present a simplified model of prostate tissue procurement that has no impact on Gleason grade, tumor stage or margin status, requires minimal specialized processing, and obtains gram amounts of fresh tissue from each radical prostatectomy specimen with a high percentage yielding cancer tissue.
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影响因子: --
作者:
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