Prenatal Maternal Objective and Subjective Stress Exposures and Rapid Infant Weight Gain.
Prenatal Maternal Objective and Subjective Stress Exposures and Rapid Infant Weight Gain.
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DOI：
10.1016/j.jpeds.2020.03.017
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发表时间：
2020-07
期刊：
影响因子：
--
通讯作者：
Bush NR
中科院分区：
文献类型：
--
作者：
Felder JN;Epel E;Coccia M;Cordeiro A;Laraia B;Adler N;Coleman-Phox K;Bush NR
目的：探讨3种产前应激暴露与婴儿体重快速增加的关系。参与者是162名母子双方，他们来自一项非随机对照试验，该试验评估了一项减少妇女压力和过度妊娠体重增加的产前干预措施，并随后对后代结果进行了纵向观察研究。参与者主要是低收入和种族或少数民族，母亲在怀孕前超重或肥胖。主要暴露是怀孕期间的客观压力暴露(应激性生活事件的数量)和主观痛苦(母亲感受到的压力和抑郁症状)。主要结果是出生到6个月的婴儿体重迅速增加，通过出生记录和个人人体测量进行评估。总体而言，28%的样本(N=40)符合婴儿体重快速增加的标准。在调整后的模型中，暴露于产前应激性生活事件与婴儿体重快速增加的几率增加相关(OR 1.40，95%CI 1.07-1.83，P=.014)。无论是产前知觉应激(OR 0.47，95%CI 0.16~1.37，P=0.17)还是抑郁症状(OR 0.89，95%CI 0.76~1.03，P=0.13)均与婴儿体重快速增加无关。女性在怀孕期间每经历一次额外的压力生活事件，婴儿体重迅速增加的几率就会增加40%。未来的研究应该评估以减少应激事件暴露为重点的产前干预是否能防止婴儿体重迅速增加。
To evaluate the associations between 3 prenatal stress exposures and rapid infant weight gain. Participants were 162 maternal–child dyads drawn from a nonrandomized controlled trial evaluating a prenatal intervention for reducing women’s stress and excessive gestational weight gain and subsequent longitudinal observational study of offspring outcomes. Participants were predominantly low-income and racial or ethnic minorities, and mothers were overweight or obese prepregnancy. Primary exposures were objective stress exposures (number of stressful life events) and subjective distress (maternal perceived stress and depressive symptoms) during pregnancy. The primary outcome was rapid infant weight gain from birth to 6 months, assessed via birth records and in-person anthropometry measurements. In total, 28% of the sample (N = 40) met criteria for rapid infant weight gain. In adjusted models, exposure to prenatal stressful life events was associated with increased odds of rapid infant weight gain (OR 1.40, 95% CI 1.07–1.83, P = .014). Neither prenatal perceived stress (OR 0.47, 95% CI 0.16–1.37, P = .17) nor depressive symptoms (OR 0.89, 95% CI 0.76–1.03, P = .13) were significantly associated with rapid infant weight gain. Each additional stressful life event a woman experienced during pregnancy was associated with 40% greater odds of rapid infant weight gain. Future research should evaluate whether prenatal interventions that focus on reducing exposure to stressful events prevent rapid infant weight gain.
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DOI：
10.1186/1476-069x-11-42
发表时间：
2012-06-27
期刊：
Environmental health : a global access science source
影响因子：
--
作者：
Barouki R;Gluckman PD;Grandjean P;Hanson M;Heindel JJ
通讯作者：
Heindel JJ
影响因子：
5.1
作者：
Braungart-Rieker, Julia M.;Lefever, Jennifer Burke;Moore, Elizabeth S.
通讯作者：
Moore, Elizabeth S.
影响因子：
3.6
作者：
Dancause, Kelsey Needham;Laplante, David P.;King, Suzanne
通讯作者：
King, Suzanne
影响因子：
158.5
作者：
Baker, Jennifer L.;Olsen, Lina W.;Sorensen, Thorkild I. A.
通讯作者：
Sorensen, Thorkild I. A.
影响因子：
12.7
作者：
Edmunds, Lynn S.;Sekhobo, Jackson P.;Davison, Kirsten K.
通讯作者：
Davison, Kirsten K.