Functional Plasticity Coupled With Structural Predispositions in Auditory Cortex Shape Successful Music Category Learning.
Functional Plasticity Coupled With Structural Predispositions in Auditory Cortex Shape Successful Music Category Learning.
复制标题
DOI：
10.3389/fnins.2022.897239
复制
发表时间：
2022
影响因子：
4.3
通讯作者：
Bidelman, Gavin M.
中科院分区：
文献类型：
--
作者：
Mankel, Kelsey;Shrestha, Utsav;Tipirneni-Sajja, Aaryani;Bidelman, Gavin M.
关键词：
将声音分类成有意义的组可以帮助听众更有效地处理听觉场景，是言语感知和语言发展的基础技能。然而，听觉类别如何通过学习在大脑中发展，特别是对于非语音声音（例如，（音乐）不好理解。在这里，我们要求音乐上天真的听众完成一个简短的（约20分钟）训练课程，在那里他们学会了从音程连续体（小调-大调第三段）中识别声音。我们使用多通道EEG来跟踪训练前后听觉事件相关电位（ERP）中与行为相关的神经可塑性变化。为了排除单纯的音乐训练引起的变化，研究人员对14名没有接受过音乐训练的非音乐家进行了神经效应的评估。我们还比较了个人的分类性能与结构体积的双侧Heschl的回（HG）从MRI评估学习的神经解剖学基板。行为表现显示更陡峭（即，更多的分类）识别功能在后测试中与更好的训练准确性相关。在神经水平上，学习者行为识别的改善的特点是在后测P2振幅较小，特别是在右半球。重要的是，在对照组中没有观察到与学习相关的ERP变化，排除了单纯的暴露效应。学习者也表现出更小和更薄的HG双边，表明上级分类与主要听觉脑区的结构差异。总的来说，我们的数据表明，成功的音乐声音听觉分类学习的特征是短期的功能变化（即，更大的训练后效率）的感觉编码过程叠加在预先存在的结构差异，在双边听觉皮层。
Categorizing sounds into meaningful groups helps listeners more efficiently process the auditory scene and is a foundational skill for speech perception and language development. Yet, how auditory categories develop in the brain through learning, particularly for non-speech sounds (e.g., music), is not well understood. Here, we asked musically naïve listeners to complete a brief (∼20 min) training session where they learned to identify sounds from a musical interval continuum (minor-major 3rds). We used multichannel EEG to track behaviorally relevant neuroplastic changes in the auditory event-related potentials (ERPs) pre- to post-training. To rule out mere exposure-induced changes, neural effects were evaluated against a control group of 14 non-musicians who did not undergo training. We also compared individual categorization performance with structural volumetrics of bilateral Heschl’s gyrus (HG) from MRI to evaluate neuroanatomical substrates of learning. Behavioral performance revealed steeper (i.e., more categorical) identification functions in the posttest that correlated with better training accuracy. At the neural level, improvement in learners’ behavioral identification was characterized by smaller P2 amplitudes at posttest, particularly over right hemisphere. Critically, learning-related changes in the ERPs were not observed in control listeners, ruling out mere exposure effects. Learners also showed smaller and thinner HG bilaterally, indicating superior categorization was associated with structural differences in primary auditory brain regions. Collectively, our data suggest successful auditory categorical learning of music sounds is characterized by short-term functional changes (i.e., greater post-training efficiency) in sensory coding processes superimposed on preexisting structural differences in bilateral auditory cortex.
登录
查看更多内容
影响因子：
5.7
作者：
Alho J;Green BM;May PJC;Sams M;Tiitinen H;Rauschecker JP;Jääskeläinen IP
通讯作者：
Jääskeläinen IP
影响因子：
3.7
作者：
Bidelman GM;Hutka S;Moreno S
通讯作者：
Moreno S
影响因子：
2
作者：
Atienza, M;Cantero, JL;Dominguez-Marin, E
通讯作者：
Dominguez-Marin, E
影响因子：
3.7
作者：
Ben-David, Boaz M.;Campeanu, Sandra;Alain, Claude
通讯作者：
Alain, Claude
影响因子：
4.3
作者：
Bidelman, Gavin M.;Bush, Lauren C.;Boudreaux, Alex M.
通讯作者：
Boudreaux, Alex M.