Regulatory Mechanisms of bHLH Transcription Factors in Plant Adaptive Responses to Various Abiotic Stresses.

Regulatory Mechanisms of bHLH Transcription Factors in Plant Adaptive Responses to Various Abiotic Stresses.
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DOI:
10.3389/fpls.2021.677611
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发表时间:
2021
影响因子:
5.6
通讯作者:
Pi E
Pi E
中科院分区:
生物学2区
文献类型:
--
作者:
Qian Y;Zhang T;Yu Y;Gou L;Yang J;Xu J;Pi E

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碱性螺旋-环-螺旋蛋白(bHLHs)是植物中最大的转录因子家族之一。它们已被证明参与对各种非生物胁迫的反应,如干旱、盐度、寒冷、重金属毒性、缺铁和渗透损害。bHLHs通过特异性结合胁迫相关基因启动子区的顺式元件,调控其转录表达,从而调控植物的适应性反应。本文就bHLHs的结构特点、bHLHs参与转录激活的调控机制以及bHLHs在不同胁迫下调控靶基因转录的机制进行综述。最后,随着越来越多的研究表明黄酮类化合物通常在波动环境下被诱导,本文对bHLHs调控黄酮类化合物生物合成调控植物对非生物胁迫反应的机制进行了最新的研究进展和未来的研究展望。
Basic helix-loop-helix proteins (bHLHs) comprise one of the largest families of transcription factors in plants. They have been shown to be involved in responses to various abiotic stresses, such as drought, salinity, chilling, heavy metal toxicity, iron deficiency, and osmotic damages. By specifically binding to cis-elements in the promoter region of stress related genes, bHLHs can regulate their transcriptional expression, thereby regulating the plant’s adaptive responses. This review focuses on the structural characteristics of bHLHs, the regulatory mechanism of how bHLHs are involved transcriptional activation, and the mechanism of how bHLHs regulate the transcription of target genes under various stresses. Finally, as increasing research demonstrates that flavonoids are usually induced under fluctuating environments, the latest research progress and future research prospects are described on the mechanisms of how flavonoid biosynthesis is regulated by bHLHs in the regulation of the plant’s responses to abiotic stresses.
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