Tracking the emergence of conceptual knowledge during human decision making.
Tracking the emergence of conceptual knowledge during human decision making.
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DOI：
10.1016/j.neuron.2009.07.030
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发表时间：
2009-09-24
期刊：
影响因子：
16.2
通讯作者：
Maguire, Eleanor A.
中科院分区：
文献类型：
--
作者：
Kumaran, Dharshan;Summerfield, Jennifer J.;Hassabis, Demis;Maguire, Eleanor A.
概念是智能的核心，为理解世界提供了组织原则。然而，令人惊讶的是，人们对我们如何获取和部署概念的理解很少。在这里，我们表明，一个功能耦合的电路，涉及海马和腹内侧前额叶皮层（vMPFC）的基础上出现的概念知识及其对选择行为的影响。重要的是，海马体单独支持将知识有效地转移到感知新颖的环境中。这些研究结果提供了令人信服的证据，海马支持概念学习，通过网络的离散记忆，并揭示其与下游的估值模块，如vMPFC的相互作用的性质。我们的研究为人类发现相关经验的概念结构并利用这些知识解决精确决策问题的非凡能力提供了神经生物学见解。
Concepts lie at the very heart of intelligence, providing organizing principles with which to comprehend the world. Surprisingly little, however, is understood about how we acquire and deploy concepts. Here, we show that a functionally coupled circuit involving the hippocampus and ventromedial prefrontal cortex (vMPFC) underpins the emergence of conceptual knowledge and its effect on choice behavior. Critically, the hippocampus alone supported the efficient transfer of knowledge to a perceptually novel setting. These findings provide compelling evidence that the hippocampus supports conceptual learning through the networking of discrete memories and reveal the nature of its interaction with downstream valuation modules such as the vMPFC. Our study offers neurobiological insights into the remarkable capacity of humans to discover the conceptual structure of related experiences and use this knowledge to solve exacting decision problems.
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影响因子：
5.3
作者：
Law, JR;Flanery, MA;Stark, CEL
通讯作者：
Stark, CEL
DOI：
10.1073/pnas.0404965101
发表时间：
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影响因子：
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