Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis.

Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis.
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壁剪切应力与颅内动脉瘤破裂的关联:系统评价和荟萃分析

DOI:
10.1038/s41598-017-05886-w
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发表时间:
2017-07-13
期刊:
影响因子:
4.6
通讯作者:
Li M
Li M
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Zhou G;Zhu Y;Yin Y;Su M;Li M

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评估壁剪切应力 (WSS) 大小与脑动脉瘤破裂之间的关系,并为有关 WSS 在颅内动脉瘤 (IA) 破裂中的作用的不同计算流体动力学 (CFD) 研究结果提供新的见解。对截至 2016 年 7 月 1 日所有可访问的已发表文章进行了系统电子数据库(PubMed、Medline、Springer 和 EBSCO)检索,对出版年份没有限制。对摘要、全文手稿和检索到的文章的参考文献列表进行了分析。使用随机效应荟萃分析来汇总各研究的并发症发生率。分析中纳入了 22 项研究,其中包含 1257 名动脉瘤患者的 CFD 数据。破裂动脉瘤中低 WSS (0–1.5Pa) 的发生率显着较高(比值比 [OR] 2.17;95% 置信区间 [CI],1.73–2.62)。 14 项低 WSS 研究的汇总分析显示,破裂组的平均 WSS 显着较低(0.64 vs. 1.4 Pa)(p = 0.037)。这项荟萃分析提供的证据表明,局部 WSS 降低可能是 IA 破裂的重要预测参数。
To evaluate the relationship between wall shear stress (WSS) magnitude and cerebral aneurysm rupture and provide new insight into the disparate computational fluid dynamics (CFD) findings concerning the role of WSS in intracranial aneurysm (IA) rupture. A systematic electronic database (PubMed, Medline, Springer, and EBSCO) search was conducted for all accessible published articles up to July 1, 2016, with no restriction on the publication year. Abstracts, full-text manuscripts, and the reference lists of retrieved articles were analyzed. Random effects meta-analysis was used to pool the complication rates across studies. Twenty-two studies containing CFD data on 1257 patients with aneurysms were included in the analysis. A significantly higher rate of low WSS (0–1.5 Pa) was found in ruptured aneurysms (odds ratio [OR] 2.17; 95% confidence interval [CI], 1.73–2.62). The pooled analyses across 14 studies with low WSS showed significantly lower mean WSS (0.64 vs. 1.4 Pa) (p = 0.037) in the ruptured group. This meta-analysis provides evidence that decreased local WSS may be an important predictive parameter of IA rupture.
DOI: 10.1136/neurintsurg-2014-011450
发表时间: 2016-01-01
影响因子: 4.8
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发表时间: 2008-11
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影响因子: 8.3
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