Dissociable neural correlates of item and context retrieval in the medial temporal lobes.
Dissociable neural correlates of item and context retrieval in the medial temporal lobes.
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DOI：
10.1016/j.bbr.2013.05.029
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发表时间：
2013-10-01
影响因子：
2.7
通讯作者：
Ranganath, Charan
中科院分区：
文献类型：
--
作者：
Wang, Wei-Chun;Yonelinas, Andrew P.;Ranganath, Charan
虽然人们普遍认为内侧颞叶（MTL）是情节记忆的关键，在MTL的皮质区域，如嗅周（PRc）和海马旁（PHc）的贡献，仍然没有得到解决。最近的研究已经断言，PRc支持对象和面部信息的处理，而PHc支持场景信息的处理。这些研究结果已被用来表征PRc和PHc作为重要的对象和场景的记忆，分别。然而，这些结果也是一致的想法，这些MTL区域是至关重要的刺激，无论是处理项目或上下文的记忆。由于在大多数研究中，项目和背景作为不同类型的备忘录（例如，对象的存储器与背景场景的存储器相比）。在这里，我们测试的程度不同的MTL区域参与检索的项目或上下文信息时，材料类型保持不变。参与者对分形图像进行编码，并将一个分形编码为一个项目，另一个编码为一个上下文。在测试中，他们被提示与先前研究的项目或上下文分形，并要求检索相应的联想。结果表明，在测试试验中，PRc活动增加的分形编码为项目的回忆，而PHc活动更大的分形编码为上下文的回忆。这些结果提供了直接的证据，即使当刺激类型保持不变，PRc和PHc优先参与支持项目和上下文信息的记忆，分别。
Although it is generally accepted that the medial temporal lobe (MTL) is critical for episodic memory, the contributions of cortical regions in the MTL, such as the perirhinal (PRc) and parahippocampal (PHc) cortices, remain unresolved. Recent studies have asserted that the PRc supports the processing of object and face information, whereas the PHc supports the processing of scene information. These findings have been used to characterize the PRc and PHc as being important for the memory of objects and scenes, respectively. However, these results are also consistent with the idea that these MTL regions are critical for the memory of stimuli that are processed as either items or contexts. It has been difficult to differentiate between these two accounts given that in most studies, item and context are operationalized as different types of memoranda (e.g., memory for objects compared to memory for background scenes). Here, we tested the extent to which different MTL regions are involved in the retrieval of item or context information when the material type is held constant. Participants encoded pairs of fractal images and were oriented to encode one fractal as an item and the other as a context. At test, they were cued with previously studied item or context fractals and asked to retrieve the corresponding associate. Results indicated that on test trials, PRc activity was increased during recall of fractals that were encoded as items, whereas PHc activity was greater during recall of fractals that were encoded as contexts. These results provide direct evidence that, even when stimulus type is held constant, the PRc and PHc are preferentially involved in supporting memory for item and context information, respectively.
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DOI：
10.1080/02724990444000203
发表时间：
2005-07-01
期刊：
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY SECTION B-COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子：
--
作者：
Eacott, MJ
通讯作者：
Eacott, MJ
影响因子：
16.2
作者：
Konkle T;Oliva A
通讯作者：
Oliva A
影响因子：
16.2
作者：
Bar, M;Aminoff, E
通讯作者：
Aminoff, E
影响因子：
3.7
作者：
Lee, Andy C. H.;Scahill, Victoria L.;Graham, Kim S.
通讯作者：
Graham, Kim S.
影响因子：
3.5
作者：
Litman, L.;Awipi, T.;Davachi, L.
通讯作者：
Davachi, L.