Bingchamides A and B, two novel cyclic pentapeptides from the Streptomyces bingchenggensis: fermentation, isolation, structure elucidation and biological properties
Bingchamides A and B, two novel cyclic pentapeptides from the Streptomyces bingchenggensis: fermentation, isolation, structure elucidation and biological properties
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Bingchamides A 和 B，来自宾城链霉菌的两种新型环状五肽：发酵、分离、结构解析和生物学特性
DOI：
10.1038/ja.2009.60
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发表时间：
2009-07
影响因子：
3.3
通讯作者：
Wen-Sheng Xiang
中科院分区：
文献类型：
--
作者：
Ji-Dong Wang;Xiang-Jing Wang;Ji Zhang;Wen-Sheng Xiang
Two novel cyclic pentapeptides, bingchamides A (1) and B (2), have been isolated from the organic extracts of the mycelium of Streptomyces bingchenggensis. The structures of 1 and 2 were elucidated on the basis of extensive 1D and 2D NMR, as well as HRESI-MS, electrospray ionization-MS, UV and IR spectroscopic data analysis. Bingchamides A (1) and B (2) exhibited in vitro cytotoxicity toward human colon carcinoma cell line HCT-116 with the IC 50 values of 14.1 and 18.0 g ml− 1, respectively. The bingchamides A (1) and B (2) scaffolds are probably promising structures for the development of new antitumor agents.
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影响因子：
8.8
作者：
Wijnhoven BP;Tilanus MG;Morris AG;Darnton SJ;Tilanus HW;Dinjens WN
通讯作者：
Dinjens WN
影响因子：
7.3
作者：
Otrubova, Katerina;McGuire, Kathleen L.;McAlpine, Shelli R.
通讯作者：
McAlpine, Shelli R.
影响因子：
7.3
作者：
Otrubova, Katerina;Lushington, Gerald;McAlpine, Shelli R.
通讯作者：
McAlpine, Shelli R.
DOI：
10.1016/j.bbrc.2005.12.131
发表时间：
2006-02-24
影响因子：
3.1
作者：
Ujiki, MB;Milam, B;Adrian, TE
通讯作者：
Adrian, TE
影响因子：
5.2
作者：
Davis, Melinda R.;Styers, Thomas J.;McAlpine, Shelli R.
通讯作者：
McAlpine, Shelli R.