HIV vaccine acceptability among immigrant Thai residents in Los Angeles: a mixed-method approach.
HIV vaccine acceptability among immigrant Thai residents in Los Angeles: a mixed-method approach.
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DOI：
10.1080/09540120701855375
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发表时间：
2008-11
期刊：
影响因子：
1.7
通讯作者：
Duan N
中科院分区：
文献类型：
--
作者：
Lee SJ;Brooks RA;Newman PA;Seiden D;Sangthong R;Duan N
这项研究调查了加利福尼亚州洛杉矶的泰国移民居民对艾滋病毒疫苗的接受度。我们结合了定性研究方法(焦点小组)和创新的市场研究方法(联合分析)。焦点小组探讨了与艾滋病毒疫苗可接受性相关的社会问题、关切、障碍和动机。联合分析被用来评估8种假设的HIV疫苗之间的偏好，这些疫苗具有不同的属性概况，以及各种属性对可接受性的影响。焦点小组确定了关于接受和使用预防性艾滋病毒疫苗的五个主要主题：(1)疫苗特性，如效力、身体副作用和成本，(2)对疫苗的恐惧，(3)疫苗的可接受性和乐观性，(4)社会和家庭反应，(5)行为去抑制。联合分析显示，在8种假设疫苗中，艾滋病毒疫苗的可接受性从7.4(SD=19.4)到85.2(SD=24.3)不等。可接受性最高的疫苗具有以下属性：99%的有效率，无副作用，10年保护期，对一种亚型的保护，免费，一剂注射。疫苗效力对可接受性的影响最大(51.4，p=.005)，其次是副作用(11.1，p=.005)和保护期(8.3，p=.005)。尽管有一些担忧和担忧，泰国居民认为艾滋病毒疫苗对社会和保护自己和家人免受艾滋病毒感染做出了重要贡献。然而，部分有效疫苗的可接受性可能很低，这表明需要量身定做的社会营销干预措施，可能强调集体主义而不是个人主义的重点。使用混合方法评估艾滋病毒疫苗在泰国居民中的可接受性是可行的，并应有助于在美国与其他亚太岛民进行艾滋病毒疫苗研究。
This study examined HIV vaccine acceptability among immigrant Thai residents in Los Angeles, California. We combined a qualitative research method (focus groups) with an innovative market research method (conjoint analysis). Focus groups explored social issues, concerns, barriers and motivators associated with HIV vaccine acceptability. Conjoint analysis was used to assess preferences among eight hypothetical HIV vaccines with varying attribute profiles and the impact of various attributes on acceptability. Five main themes were identified in the focus groups regarding acceptance and utilization of preventive HIV vaccines: (1) vaccine characteristics, such as efficacy, physical side-effects and cost, (2) fear of a vaccine, (3) vaccine acceptability and optimism, (4) social and family responses and (5) behavioral disinhibition. Conjoint analysis revealed HIV vaccine acceptability ranging from 7.4 (SD = 19.4) to 85.2 (SD = 24.3) across eight hypothetical vaccines. The vaccine with the highest acceptability had the following attributes: 99% efficacy, no side-effects, 10 years of protection, protects against one sub-type, free, one dose and given by injection. Vaccine efficacy had the greatest impact on acceptability (51.4, p = .005), followed by side-effects (11.1, p = .005) and duration of protection (8.3, p = .005). Despite some apprehensions and concerns, Thai residents perceived an HIV vaccine as making an important contribution to society and to protecting oneself and one’s family from HIV infection. Nevertheless, acceptability of a partially efficacious vaccine may be low, suggesting the need for tailored social marketing interventions that might emphasize a collectivistic rather than an individualistic focus. Assessing HIV vaccine acceptability using a mixed-method approach is feasible with Thai residents and should lend itself to HIV vaccine research with other Asian Pacific Islander populations in the US.
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影响因子：
3.4
作者：
Phillips, KA;Johnson, FR;Maddala, T
通讯作者：
Maddala, T
DOI：
10.1080/09540120600872711
发表时间：
2007-01-01
影响因子：
1.7
作者：
Brooks, R. A.;Newman, P. A.;Ortiz, D. J.
通讯作者：
Ortiz, D. J.
DOI：
10.1006/obhd.1994.1055
发表时间：
1994-08-01
影响因子：
4.6
作者：
HERSHEY, JC;ASCH, DA;WATERS, VV
通讯作者：
WATERS, VV
影响因子：
3.2
作者：
Kittikorn, Nilmanat;Street, Annette E.;Blackford, Jeanine
通讯作者：
Blackford, Jeanine
影响因子：
5
作者：
Vanlandingham, MJ;Im-Em, W;Saengtienchai, C
通讯作者：
Saengtienchai, C