Preschool depression: homotypic continuity and course over 24 months.
Preschool depression: homotypic continuity and course over 24 months.
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DOI：
10.1001/archgenpsychiatry.2009.97
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发表时间：
2009-08
影响因子：
--
通讯作者：
Spitznagel, Ed
中科院分区：
文献类型：
--
作者：
Luby, Joan L.;Si, Xuemei;Belden, Andy C.;Tandon, Mini;Spitznagel, Ed
儿童抑郁症是一种严重的复发性精神疾病。然而，迄今为止的研究主要集中在6岁及以上的儿童。2个独立研究样本对学龄前儿童抑郁症进行了验证。虽然有几项研究已经证明了学龄前儿童内化症状的稳定性和不良结果，但尚未有纵向数据可以告知学龄前抑郁症的过程以及它是否显示出幼儿期的同型连续性。研究学龄前抑郁症的24个月病程，以及它是否表现出同型与异型的连续性，或者是一种发育上的短暂现象。盲评、前瞻性、24个月、纵向随访研究。社区网站。306名3至6岁的学龄前儿童从社区网站招募，并过度采样抑郁症的症状。抑郁症的复发/稳定性和预测因素。基线时患有抑郁症的学龄前儿童在12个月和/或24个月后患抑郁症的可能性最高，与基线时没有抑郁症的学龄前儿童和患有其他精神疾病的学龄前儿童相比。基线时患有抑郁症的学龄前儿童更有可能在以后患抑郁症，而不是其他精神疾病。Logistic回归分析的结果表明，当控制人口统计学变量，危险因素和共病障碍，抑郁症在学龄前期间和情感障碍家族史是最强大的和显着的预测因子，后来抑郁症。学龄前抑郁症，类似于儿童抑郁症，不是一种发展短暂的综合征，而是表现出慢性和/或复发。在24个月的时间里，学龄前抑郁症的同型连续性被发现。这些结果强调了早在学龄前就识别抑郁症的临床和公共卫生的重要性。进一步跟进学龄前儿童抑郁症是必要的，以告知整个童年的纵向过程。
Childhood depression is a serious and relapsing psychiatric disorder. However, to date studies have focused mostly on children aged 6 years and older. Validation for depression in preschool children has been provided by 2 independent study samples. While several studies have demonstrated stability and poor outcomes of internalizing symptoms in preschoolers, there has not yet been longitudinal data available to inform the course of preschool depression and whether it shows homotypic continuity into early childhood. To examine the 24-month course of preschool depression and whether it showed homotypic vs heterotypic continuity or was a developmentally transient phenomenon. Blindly rated, prospective, 24-month, longitudinal follow-up study. Community sites. Three hundred six preschoolers aged 3 to 6 years recruited from community sites and oversampled for symptoms of depression. Recurrence/stability of depression and predictors of course. Preschoolers with depression at baseline had the highest likelihood of subsequent depression 12 and/or 24 months later compared with preschoolers with no baseline disorder and with those who had other psychiatric disorders. Preschoolers with depression at baseline were more likely to have later depression rather than other psychiatric disorders. Findings from a logistic regression analysis indicated that when controlling for demographic variables, risk factors, and comorbid disorders, depression during the preschool period and family history of affective disorders were the most robust and significant predictors of later depression. Preschool depression, similar to childhood depression, is not a developmentally transient syndrome but rather shows chronicity and/or recurrence. Homotypic continuity of preschool MDD during a 24-month period was found. These results underscore the clinical and public health importance of identification of depression as early as preschool. Further follow-up of preschoolers with depression is warranted to inform the longitudinal course throughout childhood.
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DOI：
10.1016/s0270-4684(85)80005-7
发表时间：
1985-01-01
期刊：
ANALYSIS AND INTERVENTION IN DEVELOPMENTAL DISABILITIES
影响因子：
--
作者：
FENSKE, EC;ZALENSKI, S;MCCLANNAHAN, LE
通讯作者：
MCCLANNAHAN, LE
影响因子：
2.9
作者：
KASHANI, JH;RAY, JS
通讯作者：
RAY, JS
DOI：
10.1111/j.1469-7610.2005.00422.x
发表时间：
2005-11-01
影响因子：
7.6
作者：
Burke, JD;Loeber, R;Rathouz, PJ
通讯作者：
Rathouz, PJ
DOI：
10.1097/01.chi.0000205705.71194.b8
发表时间：
2006-05-01
影响因子：
13.3
作者：
Egger, HL;Erkanli, A;Angold, A
通讯作者：
Angold, A
DOI：
10.1016/s0002-7138(09)60570-7
发表时间：
1985-01-01
影响因子：
13.3
作者：
KASHANI, JH;CARLSON, GA
通讯作者：
CARLSON, GA