Connecting the dots in Huntington's disease with protein interaction networks.

Connecting the dots in Huntington's disease with protein interaction networks.
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将亨廷顿病中的点与蛋白质相互作用网络联系起来。

DOI:
10.1186/gb-2005-6-3-210
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发表时间:
2005
期刊:
影响因子:
12.3
通讯作者:
Muchowski, PJ
Muchowski, PJ
中科院分区:
生物学1区
文献类型:
--
作者:
Giorgini, F;Muchowski, PJ

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Analysis of protein-protein interaction networks has identified new proteins and interactions that might be involved in the pathogenesis of the neurodegenerative disorder Huntington's disease. Analysis of protein-protein interaction networks is becoming important for inferring the function of uncharacterized proteins. A recent study using this approach has identified new proteins and interactions that might be involved in the pathogenesis of the neurodegenerative disorder Huntington's disease, including a GTPase-activating protein that co-localizes with protein aggregates in Huntington's disease patients.
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