Substance abuse and cognitive functioning in schizophrenia.
Substance abuse and cognitive functioning in schizophrenia.
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精神分裂症的药物滥用和认知功能。
DOI：
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发表时间：
1997
影响因子：
4.3
通讯作者：
D. Addington
中科院分区：
文献类型：
--
作者：
J. Addington;D. Addington
精神分裂症患者更容易滥用药物或酒精。这种脆弱性可能会干扰疾病的进程和治疗，也可能对已经受损的认知功能产生不利影响。本研究采用配对横断面设计，比较了33名滥用药物的精神分裂症患者和33名非滥用药物的精神分裂症患者的社会和认知功能以及症状。受试者在性别、年龄和教育变量上匹配，并且都是门诊患者。使用了社会功能和生活质量的衡量标准。认知功能的评估包括言语能力、注意力、执行功能以及言语和视觉记忆的测量。物质滥用者的生活质量明显较低。两组间无其他差异。对于认知功能缺乏观察到的差异，有几种解释。
Individuals with schizophrenia have an increased vulnerability to abuse drugs or alcohol. This vulnerability can interfere with the course and treatment of the disorder and may also have a detrimental effect on already compromised cognitive functioning. This study has a matched, cross-sectional design and compares the social and cognitive functioning and the symptoms of 33 schizophrenia subjects who abuse substances with 33 nonabusing schizophrenia subjects. Subjects were matched on sex, age, and education variables and were all outpatients. Measures of social functioning and quality of life were used. Assessment of cognitive functioning included measures of verbal ability, attention, executive functioning, and verbal and visual memory. Substance-abusing subjects had significantly lower quality of life. There were no other differences between the 2 groups. Several explanations are offered for the lack of observed differences in cognitive functioning.
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精神分裂症中药物滥用的患病率：人口统计学和临床相关性。
影响因子：
6.6
作者：
Mueser,KT;Yarnold,PR;Levinson,DF;Singh,H;Bellack,AS;Kee,K;Morrison,RL;Yadalam,KG
通讯作者：
Yadalam,KG
精神分裂症患者的药物滥用：临床相关性和使用原因。
DOI：
10.1176/ajp.148.2.224
发表时间：
1991
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Dixon,L;Haas,G;Weiden,PJ;Sweeney,J;Frances,AJ
通讯作者：
Frances,AJ
首发精神分裂症的治疗结果。
影响因子：
--
作者：
Lieberman,J;Jody,D;Geisler,S;Vital-Herne,J;Alvir,JM;Walsleben,J;Woerner,MG
通讯作者：
Woerner,MG
精神分裂症和药物滥用的共病：对治疗的影响。
影响因子：
5.9
作者：
Mueser,KT;Bellack,AS;Blanchard,JJ
通讯作者：
Blanchard,JJ