Parallel evolution of Batesian mimicry supergene in two Papilio butterflies, P. polytes and P. memnon.
Parallel evolution of Batesian mimicry supergene in two Papilio butterflies, P. polytes and P. memnon.
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DOI：
10.1126/sciadv.aao5416
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发表时间：
2018-04
期刊：
影响因子：
13.6
通讯作者：
Fujiwara H
中科院分区：
文献类型：
--
作者：
Iijima T;Kajitani R;Komata S;Lin CP;Sota T;Itoh T;Fujiwara H
在两种密切相关的蝴蝶物种中，雌蝶拟态的多态性是独立进化的。当模仿者模仿令人厌恶的模型时，动物的拟态保护动物免受捕食者的伤害。凤蝶的雌性限制性拟雌行为是由一个超基因位点控制的，该位点转换拟雌和非拟雌形式。在凤蝶中，最近的研究表明，一个高度多样化的区域（HDR）含有doubletex（dsx-HDR）构成的超基因与二型等位基因，并可能保持染色体倒位。在密切相关的美凤蝶，表现出类似的拟态多态性，我们进行了全基因组序列分析，在11只蝴蝶，这揭示了一个几乎相同的dsx-HDR包含三个基因（dsx，Nach样，和UXT）与二态序列严格相关的拟态/非拟态表型。除Nach-like基因在雌性后翅中的表达外，其他基因的表达均表现出与表型相关的差异。在门农青霉中的双态dsx-HDR在没有染色体倒位的情况下得以维持，这表明在这些基因中有单独的机制引起并维持等位基因趋异。在dsx-HDR中比在其他基因组区域中更丰富的转座因子和重复序列的积累可能有助于染色体重组的抑制。Dsx，Nach样，和UXT的基因树表明，模仿等位基因独立进化的两个凤蝶物种。这些结果表明，涉及上述三个基因的基因组区域已多次发散，使该区域的两个等位基因序列的功能作为发育开关的模仿多态性在两个凤蝶物种。这里揭示的表基因结构表明，独立的进化过程与不同的遗传机制，导致了平行进化的相似的女性有限的多态性的基础Baericum模仿凤蝶。
Female-limited polymorphisms underlying Batesian mimicry have evolved independently in two closely related butterfly species. Batesian mimicry protects animals from predators when mimics resemble distasteful models. The female-limited Batesian mimicry in Papilio butterflies is controlled by a supergene locus switching mimetic and nonmimetic forms. In Papilio polytes, recent studies revealed that a highly diversified region (HDR) containing doublesex (dsx-HDR) constitutes the supergene with dimorphic alleles and is likely maintained by a chromosomal inversion. In the closely related Papilio memnon, which exhibits a similar mimicry polymorphism, we performed whole-genome sequence analyses in 11 butterflies, which revealed a nearly identical dsx-HDR containing three genes (dsx, Nach-like, and UXT) with dimorphic sequences strictly associated with the mimetic/nonmimetic phenotypes. In addition, expression of these genes, except that of Nach-like in female hind wings, showed differences correlated with phenotype. The dimorphic dsx-HDR in P. memnon is maintained without a chromosomal inversion, suggesting that a separate mechanism causes and maintains allelic divergence in these genes. More abundant accumulation of transposable elements and repetitive sequences in the dsx-HDR than in other genomic regions may contribute to the suppression of chromosomal recombination. Gene trees for Dsx, Nach-like, and UXT indicated that mimetic alleles evolved independently in the two Papilio species. These results suggest that the genomic region involving the above three genes has repeatedly diverged so that two allelic sequences of this region function as developmental switches for mimicry polymorphism in the two Papilio species. The supergene structures revealed here suggest that independent evolutionary processes with different genetic mechanisms have led to parallel evolution of similar female-limited polymorphisms underlying Batesian mimicry in Papilio butterflies.
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影响因子：
64.8
作者：
Joron, Mathieu;Frezal, Lise;Jones, Robert T.;Chamberlain, Nicola L.;Lee, Siu F.;Haag, Christoph R.;Whibley, Annabel;Becuwe, Michel;Baxter, Simon W.;Ferguson, Laura;Wilkinson, Paul A.;Salazar, Camilo;Davidson, Claire;Clark, Richard;Quail, Michael A.;Beasley, Helen;Glithero, Rebecca;Lloyd, Christine;Sims, Sarah;Jones, Matthew C.;Rogers, Jane;Jiggins, Chris D.;Ffrench-Constant, Richard H.
通讯作者：
Ffrench-Constant, Richard H.
影响因子：
64.8
作者：
Dasmahapatra, Kanchon K.;Walters, James R.;Briscoe, Adriana D.;Davey, John W.;Whibley, Annabel;Nadeau, Nicola J.;Zimin, Aleksey V.;Hughes, Daniel S. T.;Ferguson, Laura C.;Martin, Simon H.;Salazar, Camilo;Lewis, James J.;Adler, Sebastian;Ahn, Seung-Joon;Baker, Dean A.;Baxter, Simon W.;Chamberlain, Nicola L.;Chauhan, Ritika;Counterman, Brian A.;Dalmay, Tamas;Gilbert, Lawrence E.;Gordon, Karl;Heckel, David G.;Hines, Heather M.;Hoff, Katharina J.;Holland, Peter W. H.;Jacquin-Joly, Emmanuelle;Jiggins, Francis M.;Jones, Robert T.;Kapan, Durrell D.;Kersey, Paul;Lamas, Gerardo;Lawson, Daniel;Mapleson, Daniel;Maroja, Luana S.;Martin, Arnaud;Moxon, Simon;Palmer, William J.;Papa, Riccardo;Papanicolaou, Alexie;Pauchet, Yannick;Ray, David A.;Rosser, Neil;Salzberg, Steven L.;Supple, Megan A.;Surridge, Alison;Tenger-Trolander, Ayse;Vogel, Heiko;Wilkinson, Paul A.;Wilson, Derek;Yorke, James A.;Yuan, Furong;Balmuth, Alexi L.;Eland, Cathlene;Gharbi, Karim;Thomson, Marian;Gibbs, Richard A.;Han, Yi;Jayaseelan, Joy C.;Kovar, Christie;Mathew, Tittu;Muzny, Donna M.;Ongeri, Fiona;Pu, Ling-Ling;Qu, Jiaxin;Thornton, Rebecca L.;Worley, Kim C.;Wu, Yuan-Qing;Linares, Mauricio;Blaxter, Mark L.;Ffrench-Constant, Richard H.;Joron, Mathieu;Kronforst, Marcus R.;Mullen, Sean P.;Reed, Robert D.;Scherer, Steven E.;Richards, Stephen;Mallet, James;McMillan, W. Owen;Jiggins, Chris D.
通讯作者：
Jiggins, Chris D.
影响因子：
0.8
作者：
Gorelick, R
通讯作者：
Gorelick, R
影响因子：
4.6
作者：
Komata S;Lin CP;Iijima T;Fujiwara H;Sota T
通讯作者：
Sota T
影响因子：
30.8
作者：
Kuepper, Clemens;Stocks, Michael;Risse, Judith E.;dos Remedios, Natalie;Farrell, Lindsay L.;Mcrae, Susan B.;Morgan, Tawna C.;Karlionova, Natalia;Pinchuk, Pavel;Verkuil, Yvonne I.;Kitaysky, Alexander S.;Wingfield, John C.;Piersma, Theunis;Zeng, Kai;Slate, Jon;Blaxter, Mark;Lank, David B.;Burke, Terry
通讯作者：
Burke, Terry