IRESite--a tool for the examination of viral and cellular internal ribosome entry sites.
IRESite--a tool for the examination of viral and cellular internal ribosome entry sites.
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DOI:
10.1093/nar/gkp981
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发表时间:
2010-01
影响因子:
14.9
通讯作者:
Pospísek M
中科院分区:
文献类型:
--
作者:
Mokrejs M;Masek T;Vopálensky V;Hlubucek P;Delbos P;Pospísek M
The IRESite (http://www.iresite.org) presents carefully curated experimental evidence of many eukaryotic viral and cellular internal ribosome entry site (IRES) regions. At the time of submission, IRESite stored >600 records. The IRESite gradually evolved into a robust tool providing (i) biologically meaningful information regarding the IRESs and their experimental background (including annotation of IRES secondary structures and IRES trans-acting factors) as well as (ii) thorough concluding remarks to stored database entries and regularly updated evaluation of the reported IRES function. A substantial portion of the IRESite data results purely from in-house bioinformatic analyses of currently available sequences, in silico attempts to repeat published cloning experiments, DNA sequencing and restriction endonuclease verification of received plasmid DNA. We also present a newly implemented tool for displaying RNA secondary structures and for searching through the structures currently stored in the database. The supplementary material contains an updated list of reported IRESs.
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DOI:
10.1093/bioinformatics/btp250
发表时间:
2009-08-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Darty K;Denise A;Ponty Y
通讯作者:
Ponty Y
DOI:
10.1073/pnas.0710650105
发表时间:
2008-03-25
影响因子:
11.1
作者:
Baranick, Brian T.;Lemp, Nathan A.;Logg, Christopher R.
通讯作者:
Logg, Christopher R.
影响因子:
64.5
作者:
Sonenberg N;Hinnebusch AG
通讯作者:
Hinnebusch AG
影响因子:
64.8
作者:
MACEJAK, DG;SARNOW, P
通讯作者:
SARNOW, P
影响因子:
15.9
作者:
Martínez-Salas E
通讯作者:
Martínez-Salas E