A Systematic Nomenclature for the Drosophila Ventral Nerve Cord.

A Systematic Nomenclature for the Drosophila Ventral Nerve Cord.
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DOI:
10.1016/j.neuron.2020.08.005
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发表时间:
2020-09-23
期刊:
影响因子:
16.2
通讯作者:
Shepherd D
Shepherd D
中科院分区:
医学1区
文献类型:
--
作者:
Court R;Namiki S;Armstrong JD;Börner J;Card G;Costa M;Dickinson M;Duch C;Korff W;Mann R;Merritt D;Murphey RK;Seeds AM;Shirangi T;Simpson JH;Truman JW;Tuthill JC;Williams DW;Shepherd D

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黑腹果蝇是一种成熟的神经科学研究模型,与生物学和医学相关。直到最近,对果蝇大脑的研究一直受到缺乏完整和统一命名的阻碍。认识到这一点,产生了一个权威的命名为成年昆虫的大脑,使用果蝇作为参考。在这里,我们将这种命名法扩展到成人胸和腹部的神经节,腹神经索(VNC),提供一个解剖学描述的果蝇神经系统的这一主要组成部分。VNC是接收和整合感觉信息的场所,并参与产生大部分构成苍蝇行为基础的运动动作。目的是为果蝇VNC创建一个与其他昆虫一致的命名法、定义和空间边界。这项工作建立了一个解剖框架,为分析VNC的功能组织提供了一个强大的工具。
Drosophila melanogaster is an established model for neuroscience research with relevance in biology and medicine. Until recently, research on the Drosophila brain was hindered by the lack of a complete and uniform nomenclature. Recognizing this, produced an authoritative nomenclature for the adult insect brain, using Drosophila as the reference. Here, we extend this nomenclature to the adult thoracic and abdominal neuromeres, the ventral nerve cord (VNC), to provide an anatomical description of this major component of the Drosophila nervous system. The VNC is the locus for the reception and integration of sensory information and involved in generating most of the locomotor actions that underlie fly behaviors. The aim is to create a nomenclature, definitions, and spatial boundaries for the Drosophila VNC that are consistent with other insects. The work establishes an anatomical framework that provides a powerful tool for analyzing the functional organization of the VNC.
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