Neonatal NIRS monitoring: recommendations for data capture and review of analytics.

Neonatal NIRS monitoring: recommendations for data capture and review of analytics.
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DOI:
10.1038/s41372-021-00946-6
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发表时间:
2021-04
期刊:
Journal of perinatology : official journal of the California Perinatal Association
影响因子:
--
通讯作者:
Chock VY
Chock VY
中科院分区:
其他
文献类型:
--
作者:
Vesoulis ZA;Mintzer JP;Chock VY

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脑损伤是新生儿面临的最严重的问题之一,许多早产儿和足月儿有脑缺氧和缺血的风险。为了开发有效的神经保护策略,必须了解脑损伤的机制基础。新生儿的脆弱状态提出了独特的研究挑战;脑血流和氧合评估的侵入性措施超过了可容忍的风险。近红外光谱(NIRS)可以安全、无创地评估脑氧合,这是脑灌注的一个相关因素,可以深入了解脑损伤相关机制。不幸的是,设备应用、记录方法和错误/伪影校正缺乏标准化,导致该领域出现断裂。在这篇文章中,我们提供了一个框架,新生儿近红外光谱研究。我们的目标是为NIRS数据采集和处理提供一个合理的基础,从而使研究之间具有更好的可比性。它还旨在作为新的NIRS研究人员的入门,并协助调查启动。
Brain injury is one of the most consequential problems facing neonates, with many preterm and term infants at risk for cerebral hypoxia and ischemia. To develop effective neuroprotective strategies, the mechanistic basis for brain injury must be understood. The fragile state of neonates presents unique research challenges; invasive measures of cerebral blood flow and oxygenation assessment exceed tolerable risk profiles. Near-infrared spectroscopy (NIRS) can safely and non-invasively estimate cerebral oxygenation, a correlate of cerebral perfusion, offering insight into brain injury-related mechanisms. Unfortunately, lack of standardization in device application, recording methods, and error/artifact correction have left the field fractured. In this article, we provide a framework for neonatal NIRS research. Our goal is to provide a rational basis for NIRS data capture and processing that may result in better comparability between studies. It is also intended to serve as a primer for new NIRS researchers and assist with investigation initiation.
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