Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation.

Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation.
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DOI:
10.1093/cid/ciaa933
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发表时间:
2021-04-26
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Hollingsworth TD
Hollingsworth TD
中科院分区:
其他
文献类型:
--
作者:
Toor J;Adams ER;Aliee M;Amoah B;Anderson RM;Ayabina D;Bailey R;Basáñez MG;Blok DJ;Blumberg S;Borlase A;Rivera RC;Castaño MS;Chitnis N;Coffeng LE;Crump RE;Das A;Davis CN;Davis EL;Deiner MS;Diggle PJ;Fronterre C;Giardina F;Giorgi E;Graham M;Hamley JID;Huang CI;Kura K;Lietman TM;Lucas TCD;Malizia V;Medley GF;Meeyai A;Michael E;Porco TC;Prada JM;Rock KS;Le Rutte EA;Smith ME;Spencer SEF;Stolk WA;Touloupou P;Vasconcelos A;Vegvari C;de Vlas SJ;Walker M;Hollingsworth TD

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由于新冠肺炎大流行,许多被忽视的热带病关键活动被推迟。这一障碍出现之际,非关税壁垒正在朝着2030年的雄心勃勃的目标迈进。对几种非传染性疾病,即冈比亚昏睡病、淋巴丝虫病、盘尾丝虫病、血吸虫病、土壤传播蠕虫硫酶(STH)、沙眼和内脏利什曼病的数学模拟表明,这种干扰的影响将因疾病而异。节目面临着死灰复燃的风险,在高传播率地区,这将是最快的。此外,在大规模用药疾病中,血吸虫病、性传播感染和沙眼可能会出现较快的复发。发现病例的疾病(冈比亚病、昏睡病和内脏利什曼病)可能会发现较少的病例,但可能面临不断增加的新感染率。然而,一旦项目能够恢复,就有办法减轻影响,加快实现2030年目标的进程。新冠肺炎疫情扰乱了被忽视的热带病项目。模型显示,这一影响将因疾病而异。一旦重新采取干预措施,就有机会缓解拖延,加快实现2030年目标的进展。
Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when the NTDs are progressing towards their ambitious goals for 2030. Mathematical modelling on several NTDs, namely gambiense sleeping sickness, lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiases (STH), trachoma, and visceral leishmaniasis, shows that the impact of this disruption will vary across the diseases. Programs face a risk of resurgence, which will be fastest in high-transmission areas. Furthermore, of the mass drug administration diseases, schistosomiasis, STH, and trachoma are likely to encounter faster resurgence. The case-finding diseases (gambiense sleeping sickness and visceral leishmaniasis) are likely to have fewer cases being detected but may face an increasing underlying rate of new infections. However, once programs are able to resume, there are ways to mitigate the impact and accelerate progress towards the 2030 goals. The COVID-19 pandemic has disrupted neglected tropical disease programs. Modelling shows the impact of this will vary across diseases. Once interventions are reintroduced, there are opportunities for mitigating the delay and accelerating progress towards the 2030 goals.
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