Feasibility study of a unilateral RF array coil for MR-scintimammography.

Feasibility study of a unilateral RF array coil for MR-scintimammography.
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DOI:
10.1088/0031-9155/56/21/004
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发表时间:
2011-11-07
影响因子:
3.5
通讯作者:
Nalcioglu O
Nalcioglu O
中科院分区:
工程技术2区
文献类型:
--
作者:
Ha S;Hamamura MJ;Roeck WW;Hugg J;Wagenaar DJ;Meier D;Patt BE;Nalcioglu O

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尽管具有很高的灵敏度,但磁共振成像(MRI)在乳腺癌诊断中的可变特异性可能导致不必要的活组织检查和过度治疗。扫描成像(SMM)可作为MRI的补充,提高诊断特异性。MRI和SMM的协同结合(MRSMM)可以获得MRI的高灵敏度和SMM的高特异性。开发这种双模态系统需要将射频线圈和辐射探测器集成在强磁场中,而不会产生明显的相互干扰。在这项研究中,我们开发并测试了一种专门用于MRSMM成像的单侧乳房阵列线圈。通过仿真和实验测量,研究了安装在专用射频和伽马射线屏蔽装置内的碲化镉锌(CZT)探测器的电磁(EM)场、比吸收比(SAR)和射频线圈参数。采用一体化的MRSMM系统,同时获得乳房假体的MR和SMM图像。这项工作,我们认为,代表了一个重要的一步,为一个工作的MRSMM系统的制造。
Despite its high sensitivity, the variable specificity of magnetic resonance imaging (MRI) in breast cancer diagnosis can lead to unnecessary biopsies and over-treatment. Scintimammography (SMM) could potentially supplement MRI for improving the diagnostic specificity. The synergistic combination of MRI and SMM (MRSMM) could result in both high sensitivity from MRI and high specificity from SMM. Development of such a dual-modality system requires the integration of a radio frequency (RF) coil and radiation detector in a strong magnetic field without significant mutual interference. In this study, we developed and tested a unilateral breast array coil specialized for MRSMM imaging. The electromagnetic (EM) field, specific absorption ratio (SAR), and RF coil parameters with cadmium-zinc-telluride (CZT) detectors encapsulated in specialized RF and gamma-ray shielding mounted within the RF coil were investigated through simulation and experimental measurements. Simultaneous MR and SMM images of a breast phantom were also acquired using the integrated MRSMM system. This work, we feel, represents an important step toward the fabrication for a working MRSMM system.
DOI: 10.1088/0031-9155/55/6/002
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