MRI-based mechanical competence assessment of bone using micro finite element analysis (micro-FEA): Review.

MRI-based mechanical competence assessment of bone using micro finite element analysis (micro-FEA): Review.
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DOI:
10.1016/j.mri.2022.01.009
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发表时间:
2022-05
影响因子:
2.5
通讯作者:
Chang EY
Chang EY
中科院分区:
医学4区
文献类型:
--
作者:
Jerban S;Alenezi S;Afsahi AM;Ma Y;Du J;Chung CB;Chang EY

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双能X线吸收法(DEXA)测量的面骨矿物质密度(aBMD)和体积骨矿物质密度(vBMD)在评估骨力学性能和预测骨折方面能力有限。由于骨具有异质性和各向异性,例如依赖于加载方向、解剖位置和样本尺寸,预测骨结构的宏观力学行为一直具有挑战性。磁共振成像(MRI)已被引入作为一种有前景的方法,可与有限元分析(FEA)相结合用于评估骨力学性能。这篇综述文章介绍了一些研究,这些研究将基于MRI的微有限元分析作为一种潜在的非侵入性方法来预测骨力学性能,并在不接触电离辐射的情况下促进骨折风险评估。具体而言,讨论了使用间接和直接骨成像进行有限元分析的步骤、应用和未来潜力。
Areal bone mineral density (aBMD) from dual-energy x-ray absorptiometry (DEXA) and volumetric bone mineral density (vBMD) have demonstrated limited capabilities in the evaluation of bone mechanical competence and prediction of bone fracture. Predicting the macroscopic mechanical behavior of the bone structure has been challenging because of the heterogeneous and anisotropic nature of bone, such as the dependencies on loading direction, anatomical location, and sample dimensions. Magnetic resonance imaging (MRI) has been introduced as a promising modality that can be coupled with finite element analysis (FEA) for the assessment of bone mechanical competence. This review article describes studies investigating MRI-based micro-FEA as a potential non-invasive method to predict bone mechanical competence and facilitate bone fracture risk estimation without exposure to ionizing radiation. Specifically, the steps, applications, and future potential of FEA using indirect and direct bone imaging are discussed.
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