The Relationship between Subjective Symptoms and Quality of Life in Conjunctivochalasis Patients.
The Relationship between Subjective Symptoms and Quality of Life in Conjunctivochalasis Patients.
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DOI：
10.3390/diagnostics11020179
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发表时间：
2021-01-27
期刊：
影响因子：
--
通讯作者：
Kinoshita S
中科院分区：
文献类型：
--
作者：
Komuro A;Yokoi N;Kato H;Sonomura Y;Sotozono C;Kinoshita S
本研究的目的是评估结膜松弛症（CCh）和干眼症（DE）患者主观症状的差异，并探讨主观症状与生活质量（QOL）之间的关系。在 75 名 CCh 患者的 75 只眼睛和 122 名 DE 患者的 122 只眼睛中，根据与症状相关的机制（ITF：泪膜不稳定、IF：摩擦力增加、R：反射和 DTC：泪液清除延迟）将 12 种主观症状分为四组，使用视觉模拟量表（VAS）进行评估。采用干眼相关生活质量评分（DEQS）问卷评估与DE症状相关的15个项目及其对日常生活的影响，将总体生活质量受损程度计算为生活质量评分。评估总 VAS 评分与 QOL 评分之间的相关性。 CCh和DE患者的主观症状存在显着差异，包括眼睛干涩、疼痛、流泪对光敏感和眼睑沉重，而CCh患者流泪程度更高。 CCh 患者的 QOL 评分与总 VAS 评分、ITF 和 IF 之间存在显着的强相关性。 CCh 患者的生活质量很大程度上取决于泪膜稳定性下降和眨眼时摩擦力增加。
The purpose of this study was to evaluate the differences in subjective symptoms between patients with conjunctivochalasis (CCh) and dry eye (DE), and examine the relationship between subjective symptoms and quality of life (QOL). In 75 eyes of 75 CCh patients and 122 eyes of 122 DE patients, 12 subjective symptoms classified into four groups depending on the mechanisms associated with symptoms (ITF: instability of tear film, IF: increased friction, R: reflex, and DTC: delayed tear clearance) were evaluated by use of a visual analogue scale (VAS). Fifteen items related to DE symptoms and their influence on daily life were evaluated by use of the dry eye-related quality-of-life score (DEQS) questionnaire, with overall degree of QOL impairment calculated as a QOL score. The correlation between the Total VAS score and QOL score were evaluated. Between the CCh and DE patients, significant differences in subjective symptoms were found in eye dryness, pain, tearing sensitivity to light, and heavy eyelids, while tearing was higher in CCh. A significant strong correlation was found between QOL score and Total VAS score, ITF, and IF in CCh patients. The QOL of CCh patients is strongly determined by decreased tear-film stability and increased friction during blinking.
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