Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study.
Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study.
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代谢综合征患者中25-羟基维生素D状态的预测因素：一项横断面研究。
DOI：
10.1186/s13098-018-0346-1
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发表时间：
2018
影响因子：
4.8
通讯作者：
Pedrosa LFC
中科院分区：
文献类型：
--
作者：
Aquino SLS;da Cunha ATO;Pereira HT;Freitas EPS;Fayh APT;Lima JG;Lima SCVC;Sena-Evangelista KCM;Pedrosa LFC
The risk of metabolic syndrome can be influenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the influence of environmental, biological, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome. This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years. The 25OHD concentration was considered the dependent variable; independent variables included age, sex, skin color, use of sunscreen, skin type, sun exposure score, ultraviolet radiation index, geographic location, season, body mass index, waist:hip ratio, waist circumference, parathyroid hormone level, total serum calcium level, and calcium and vitamin D intake. The average vitamin D in individuals evaluated in summer 32 ± 10 ng/mL was greater than in the winter 26 ± 8 ng/mL (p < 0.017). HDL-cholesterol was the only component of the MetS that differed significantly between the seasons (p < 0.001), showing higher concentrations in autumn 45 ± 8 mg/dL than in summer 35 ± 8 mg/dL. In the multiple regression model, gender, WHR, sun exposure score, and winter vs. summer explained 10% of the variation in 25OHD concentration (p = 0.004). Sex, waist:hip ratio, sun exposure, and summer season were predictors of 25OHD status among individuals with metabolic syndrome. HDL-cholesterol was the only component of metabolic syndrome that differed significantly between the seasons. The online version of this article (10.1186/s13098-018-0346-1) contains supplementary material, which is available to authorized users.
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影响因子：
5.4
作者：
Kamezaki, Fumihiko;Sonoda, Shinjo;Otsuji, Yutaka
通讯作者：
Otsuji, Yutaka
影响因子：
4.8
作者：
Miñambres I;Sánchez-Quesada JL;Sánchez-Hernández J;Rodríguez J;de Leiva A;Pérez A
通讯作者：
Pérez A
影响因子：
5.1
作者：
Chen, Shui-Hu;Jen, I-An;Chou, Pesus
通讯作者：
Chou, Pesus
影响因子：
4.7
作者：
Jorde, Rolf;Grimnes, Guri
通讯作者：
Grimnes, Guri
影响因子：
5.8
作者：
Holick, Michael F.;Binkley, Neil C.;Weaver, Connie M.
通讯作者：
Weaver, Connie M.